Spectrophotometric assay of dipyrone in pharmaceutical preparations via oxidative coupling reaction with m-toluidine and potassium hexacyanoferrate (III)
Joint Authors
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 21, Issue 2 (30 Jun. 2008), pp.36-45, 10 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2008-06-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract EN
A simple, rapid and highly sensitive spectrophotometric method has been described for the determination of dipyrone in a bulk and in dosage forms.
The method depends on the organic oxidative coupling reaction of dipyrone with m-toluidine in the presence of potassium hexacyanoferrate (III) in aqueous solution to form purple product measured at 530 nm.
Beer’s law is obeyed in the concentration range 0.4-10.0 μ g.ml-1 with accuracy (average recovery) of 99.71% and precision (RSD) is less than 2%.
The molar absorptivity is 40770 l.mol-1.cm-1 with LOD 0.051 μ g.ml-1 and LOQ 0.167 μ g.ml-1.
The analytical results agree favourably with official method (iodimetric method) and also with certified values.
American Psychological Association (APA)
Salih, E. S.& al-Sharuk, M. M.. 2008. Spectrophotometric assay of dipyrone in pharmaceutical preparations via oxidative coupling reaction with m-toluidine and potassium hexacyanoferrate (III). al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 21, no. 2, pp.36-45.
https://search.emarefa.net/detail/BIM-622452
Modern Language Association (MLA)
Salih, E. S.& al-Sharuk, M. M.. Spectrophotometric assay of dipyrone in pharmaceutical preparations via oxidative coupling reaction with m-toluidine and potassium hexacyanoferrate (III). al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 21, no. 2 (Jun. 2008), pp.36-45.
https://search.emarefa.net/detail/BIM-622452
American Medical Association (AMA)
Salih, E. S.& al-Sharuk, M. M.. Spectrophotometric assay of dipyrone in pharmaceutical preparations via oxidative coupling reaction with m-toluidine and potassium hexacyanoferrate (III). al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2008. Vol. 21, no. 2, pp.36-45.
https://search.emarefa.net/detail/BIM-622452
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 44-45
Record ID
BIM-622452