Synthesis of some substituted benzoxazole [3, 4-b] imidazoles
Author
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 21, Issue 3 (30 Sep. 2008), pp.14-22, 9 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2008-09-30
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
In this paper the synthesis of 4-substituted benzoxazole [3,4-b] imidazole (9,10) and 4-aryl hexahydrobenzoxazole [3,4-b] imidazole (13,14) is reported.
Glycine was treated with benzoyl chloride or p-nitrobenzoyl chloride to give N-aroyl glycine (1,2), the reaction of N-aroyl glycine with thionyl chloride followed by treatment the product (3,4) with ammonium hydroxide to give N-aroyl glycine amide (5,6).
Treatment of the amide with 1-bromocyclohexanone gave N-methylene-2-hexahydrobenzoxazole) arylamide (7,8), cyclization of this gave product (9,10), whereas the compounds (13,14) was synthesized from o-aminophenol and the acid chlorides to give N-methylene (2-benzoxazole) aryl amide (11,12) which cyclized with phosphorous oxychloride to give the products (13,14).
The structure of all synthesized compounds were confirmed by physical and spectral data.
American Psychological Association (APA)
al-Jawharji, Yasir S.. 2008. Synthesis of some substituted benzoxazole [3, 4-b] imidazoles. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 21, no. 3, pp.14-22.
https://search.emarefa.net/detail/BIM-623044
Modern Language Association (MLA)
al-Jawharji, Yasir S.. Synthesis of some substituted benzoxazole [3, 4-b] imidazoles. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 21, no. 3 (Sep. 2008), pp.14-22.
https://search.emarefa.net/detail/BIM-623044
American Medical Association (AMA)
al-Jawharji, Yasir S.. Synthesis of some substituted benzoxazole [3, 4-b] imidazoles. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2008. Vol. 21, no. 3, pp.14-22.
https://search.emarefa.net/detail/BIM-623044
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 22
Record ID
BIM-623044