Synthesis of some atophan derivatives

Abstract EN

The research was concerned with preparation and characterization of some esters (2-4) derived from atophan (2-phenyl cinchoninic acid).

These esters were converted to the corresponding carboxamide by their reaction with ethylene diamine.

This reaction may be follow either one of three path ways.

The first gives the monocarboxamide (5), whereas the second gives the dicarboxamide (6), while the last one gives a heterocyclic product (7).

All the synthesized compounds, have been characterized by physical and infrared and electronic spectral means.