GC-MS analysis and biological evaluation of essential oil of Zanthoxylum rhesta (Roxb.) DC pericarp
Other Title(s)
تحليل GC-MS و التقييم البيولوجي للزيت العطري من قشرة Zanthoxylum rhetsa (Roxb.) Dvm
Joint Authors
Abu Hamdah, Sawsan
Shakya, Ashok Kumar
Naik, Rajashri Ramakrishan
Khalaf, Numan Abd al-Karim
Urayqat, Ghalib Ali
Maraqah, Anwar Diyab
Source
Jordan Journal of Pharmaceutical Sciences
Issue
Vol. 8, Issue 3 (31 Dec. 2015), pp.181-193, 13 p.
Publisher
University of Jordan Deanship of Academic Research (DAR)
Publication Date
2015-12-31
Country of Publication
Jordan
No. of Pages
13
Main Subjects
Abstract EN
The present study reports the chemical composition, antioxidant, antibacterial, antidiarrheal as well as the spasmolytic activity of Zanthoxylum rhetsa (DC) essential oil, fractionated oil and its principal constituent (Terpinen-4-ol).
The constituents of essential oil were characterized by GC-FID and GC-MS.
The pharmacological and biological activities of oil, its fraction and principal constituent were carried out in-vivo and in-vitro.
The oil was rich in a group of monoterpene family, constituted mainly of terpinen-4-ol (25.43%), sabinene (16.50%), β-pinene (10.4%), α-Terpineol (7.63%), γ-Terpinene (5.64%), α-pinene (4.33%), and linalool (3.25%).
The antioxidant capacities of the oil, fractions and terpinen-4-ol were assessed by using spectrophotometry to measure free radical scavenger 2,2-diphenyl-1-picrylhydrazyl (DPPH).
Furthermore, the oil, its fractions and terpinen-4-ol exhibited appreciable antioxidant, antibacterial, antidiarrheal and non-selective spasmolytic activity.
The study suggests that the oil and its main active constituent (terpinen-4-ol) of the studied plant would have high potential in the treatment of stress and gastrointestinal diseases.
American Psychological Association (APA)
Naik, Rajashri Ramakrishan& Shakya, Ashok Kumar& Khalaf, Numan Abd al-Karim& Abu Hamdah, Sawsan& Urayqat, Ghalib Ali& Maraqah, Anwar Diyab. 2015. GC-MS analysis and biological evaluation of essential oil of Zanthoxylum rhesta (Roxb.) DC pericarp. Jordan Journal of Pharmaceutical Sciences،Vol. 8, no. 3, pp.181-193.
https://search.emarefa.net/detail/BIM-623973
Modern Language Association (MLA)
Naik, Rajashri Ramakrishan…[et al.]. GC-MS analysis and biological evaluation of essential oil of Zanthoxylum rhesta (Roxb.) DC pericarp. Jordan Journal of Pharmaceutical Sciences Vol. 8, no. 3 (2015), pp.181-193.
https://search.emarefa.net/detail/BIM-623973
American Medical Association (AMA)
Naik, Rajashri Ramakrishan& Shakya, Ashok Kumar& Khalaf, Numan Abd al-Karim& Abu Hamdah, Sawsan& Urayqat, Ghalib Ali& Maraqah, Anwar Diyab. GC-MS analysis and biological evaluation of essential oil of Zanthoxylum rhesta (Roxb.) DC pericarp. Jordan Journal of Pharmaceutical Sciences. 2015. Vol. 8, no. 3, pp.181-193.
https://search.emarefa.net/detail/BIM-623973
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 191-192
Record ID
BIM-623973