Hepatitis c virus antibodies in dialysis patients in Tunisia : a single center study
Joint Authors
Gorgi, Y.
Ben Maiz, Hedi
Sassi, F.
Ayed, K.
Ben Abd Allah, T.
Lamouchi, A.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 11, Issue 2 (30 Apr. 2000), pp.218-222, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2000-04-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Fifty-eight patients on maintenance hemodialysis in a dialysis unit at Tunis, Tunisia were tested for anti-hepatitis C virus (anti-HCV) antibodies by second generation ELISA test, and for HCV-RNA by nested reverse transcriptase polymerase chain reaction (RT-PCR) of 5' non-coding region.
Specificity of the antibodies was confirmed by immunoblot test.
HCV genotype was defined using INNO-LIPA test.
Twenty-seven out of 58 patients (46.5 %) were reactive by ELISA.
Transaminase levels were assessed over a six-month period and showed normal average values.
Fourteen of the 27 anti-HCV positive patients (51 %) were positive by RT-PCR.
Type 1b HCV genotype was the most prevalent, seen in all the dialysis patients and one patient in addition, was coinfected with genotype 4.
There was a significant correlation between the duration on dialysis (over five years) and the prevalence of anti-HCV-positive patients (P < 0.005) while no correlation existed between the number of blood transfusions and the presence of anti- HCV antibodies.
The present study illustrates the high prevalence of HCV infection among Tunisian dialysis patients (51 %) and indicates that the spread may be nosocomial rather than transfusion-related.
American Psychological Association (APA)
Sassi, F.& Gorgi, Y.& Ayed, K.& Ben Abd Allah, T.& Lamouchi, A.& Ben Maiz, Hedi. 2000. Hepatitis c virus antibodies in dialysis patients in Tunisia : a single center study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 11, no. 2, pp.218-222.
https://search.emarefa.net/detail/BIM-62545
Modern Language Association (MLA)
Gorgi, Y.…[et al.]. Hepatitis c virus antibodies in dialysis patients in Tunisia : a single center study. Saudi Journal of Kidney Diseases and Transplantation Vol. 11, no. 2 (Apr. 2000), pp.218-222.
https://search.emarefa.net/detail/BIM-62545
American Medical Association (AMA)
Sassi, F.& Gorgi, Y.& Ayed, K.& Ben Abd Allah, T.& Lamouchi, A.& Ben Maiz, Hedi. Hepatitis c virus antibodies in dialysis patients in Tunisia : a single center study. Saudi Journal of Kidney Diseases and Transplantation. 2000. Vol. 11, no. 2, pp.218-222.
https://search.emarefa.net/detail/BIM-62545
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 221-222
Record ID
BIM-62545