Spectrum of glomerulonephritis in Egypt
Joint Authors
Barsoum, Rashad
Francis, Majdi R.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 11, Issue 3 (30 Jun. 2000), pp.421-429, 9 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2000-06-30
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Topics
Abstract EN
Identification of the profile of glomerular disease in a particular geographical region is of fundamental academic, clinical and epidemiological importance.
It helps in the recognition of specific risk factors and subsequent planning for adequate prevention.
In the present study, 1234 consecutive renal biopsies referred to the nephropathology team of Cairo University over two years were retrospectively analyzed.
The main indications for biopsy included nephrotic syndrome, persistent sub-nephrotic proteinuria, recurrent hematuria, suspected secondary hypertension, lupus nephritis and acute and chronic renal failure of undetermined etiology.
Proliferative forms of glomerulonephritis [GN] (32.1 %) and focal and segmental glomerulosclerosis [FSGS] were the most prevalent lesions among patients with the nephrotic syndrome (22.6 %).
In subjects with subnephrotic proteinuria, FSGS was the principal lesion followed by proliferative lesions.
Although all forms of GN were encountered in those presenting with recurrent hematuria, mesangioproliferative GN and FSGS were significantly more frequent.
IgA glomerular deposits were detected in 9.8 % of all GNs and 15 % of those presenting with hematuria.
One half of the biopsies obtained for the assessment of suspected secondary hypertension showed only changes compatible with the effect of hypertension per se, i.e.
nephroangiosclerosis.
On the other hand, a parenchymal renal lesion was found in 52.9 % of biopsies.
The common glomerular pathologies in patients with lupus nephritis were Classes III and IV.
Among patients with chronic renal failure, the predominant lesion was chronic interstitial nephritis (32.6 %).
An acute interstitial inflammatory element was also detected in 8.4 % of cases.
About one third of the biopsies obtained for acute renal failure showed acute tubular (11 %) or cortical (13.2 %) necrosis.
Another third showed vasculitis (17.6 %) or acute interstitial nephritis (14.3 %), and the remaining showed chronic lesions in which the rapid deterioration was probably functional.
American Psychological Association (APA)
Barsoum, Rashad& Francis, Majdi R.. 2000. Spectrum of glomerulonephritis in Egypt. Saudi Journal of Kidney Diseases and Transplantation،Vol. 11, no. 3, pp.421-429.
https://search.emarefa.net/detail/BIM-62801
Modern Language Association (MLA)
Barsoum, Rashad& Francis, Majdi R.. Spectrum of glomerulonephritis in Egypt. Saudi Journal of Kidney Diseases and Transplantation Vol. 11, no. 3 (Dec. 2000), pp.421-429.
https://search.emarefa.net/detail/BIM-62801
American Medical Association (AMA)
Barsoum, Rashad& Francis, Majdi R.. Spectrum of glomerulonephritis in Egypt. Saudi Journal of Kidney Diseases and Transplantation. 2000. Vol. 11, no. 3, pp.421-429.
https://search.emarefa.net/detail/BIM-62801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 429
Record ID
BIM-62801