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Multi lamellar vesicles (Mlvs) liposomes preparation by thin film hydration technique
Other Title(s)
تحضير كريات اللايبوسومية متعددة الصفائح بواسطة طريقة هدرجة الفلم الرقيق
Joint Authors
al-Rabii, Mahdi Salih
al-Zubaydi, Labib Ahmad
Abd Allah, Taghrid Subayh
Source
Engineering and Technology Journal
Issue
Vol. 32, Issue 3B(s) (31 Mar. 2014), pp.550-560, 11 p.
Publisher
Publication Date
2014-03-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract EN
In the present research the development of liposomes by studying various processes as well as formulation related factors such as effect of cholesterol, effect of alkyl chain length of lipids which may affect the size, shape and encapsulation efficiency of liposomes was reported.
Cholesterol and phospholipids were studied by Fourier transform infrared (FTIR) spectroscopy.
From scanning electron micrographs, the liposomes appeared in various figures, the sizes of prepared liposomal particles varied in the range of 0.147-0.412 um (147- 412) nm and most of them were multilamellar structures.
The vesicle size was found to be varied from 0.147 to 0.412 um.
The liposomes were photographed using scanning electron microscope.
Vesicles were found to be spherical in shape.
Analysis of vesicle size was carried out of each formulation code and the size was found to be reproducible.
FT-IR is very useful tool for detecting chemical changes, chemical structures and the thermodynamic of phase transitions and conformational changes in biological systems.
Frequency shifts in different regions (symmetric, anti-symmetric stretching or bending, scissoring) or changes in the widths of the corresponding peaks can be used to extract information about various physicochemical processes taking place preparation.
This research review the development of liposomes, and speculates optimistically about some future applications.
American Psychological Association (APA)
al-Zubaydi, Labib Ahmad& al-Rabii, Mahdi Salih& Abd Allah, Taghrid Subayh. 2014. Multi lamellar vesicles (Mlvs) liposomes preparation by thin film hydration technique. Engineering and Technology Journal،Vol. 32, no. 3B(s), pp.550-560.
https://search.emarefa.net/detail/BIM-628475
Modern Language Association (MLA)
al-Zubaydi, Labib Ahmad…[et al.]. Multi lamellar vesicles (Mlvs) liposomes preparation by thin film hydration technique. Engineering and Technology Journal Vol. 32, no. 3B(s) (2014), pp.550-560.
https://search.emarefa.net/detail/BIM-628475
American Medical Association (AMA)
al-Zubaydi, Labib Ahmad& al-Rabii, Mahdi Salih& Abd Allah, Taghrid Subayh. Multi lamellar vesicles (Mlvs) liposomes preparation by thin film hydration technique. Engineering and Technology Journal. 2014. Vol. 32, no. 3B(s), pp.550-560.
https://search.emarefa.net/detail/BIM-628475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 559-560
Record ID
BIM-628475