![](/images/graphics-bg.png)
Validity of magnetic resonance image and HLA-B27 in early detection of sacroiliitis in Egyptian spondyloarthropathic patients
Joint Authors
Ibrahim, Muhammad
Ali, Amal
Darwish, Ayman
Hamdi, Lamya
Ali, Fatimah
al-Sharif, Ruhiyah R.
Source
Egyptian Rheumatology and Rehabilitation
Issue
Vol. 42, Issue 3 (30 Sep. 2015), pp.137-144, 8 p.
Publisher
The Egyptian Society for Rheumatology and Rehabilitation
Publication Date
2015-09-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
Objective The aim of this study was to compare the validity of MRI in the early detection of sacroiliitis with laboratory findings of human leukocyte antigen-B27 (HLA-B27), conventional radiography, and clinical assessment.
Participants and methods Sixty patients with spondyloarthropathy (group II) with duration of illness less than 2 years and 20 healthy controls (group I) were included in this study.
Both groups were subjected to assessment of history, clinical examination, and laboratory investigations (erythrocyte sedimentation rate, C-reactive protein titer, rheumatoid factor, HLA-B27).
Conventional radiography and MRI of the sacroiliac joints were performed.
Spondyloarthropathic patients were divided according to MRI as follows: group IIA, which included patients with sacroiliitis, and group IIB, which included patients without sacroiliitis.
Results In our study, ankylosing spondylitis was diagnosed in 22 (36.6%) patients, followed by undifferentiated spondyloarthropathy in 12 (20%) patients, reactive arthritis in 10 (16.7%) patients, psoriatic arthropathy in 10 (16.7%) patients, and enteropathic arthropathy in six (10%) patients.
Evidence of sacroiliitis was found in 66.6% (40/60) of patients by MRI, which was higher than the result obtained by plain radiography 20% (12/60).
HLA-B27 positivity found in 53.3% (32/60) of patients.
There was a significant difference between the two groups in HLA-B27 and radiological sacroiliitis; there was no sacroiliitis in the control group.
MRI showed sacroiliitis even in patients with no inflammatory back pain.
There was a highly statistically significant difference between patient subgroups in disease duration (P = 0.001) and primary complaints and clinical sacroiliitis (P = 0.001).
Conclusion MRI is the preferred modality in the detection of early sacroiliitis in spondyloarthropathy and HLA-B27 positivity is a highly useful predictor of early sacroiliitis
American Psychological Association (APA)
al-Sharif, Ruhiyah R.& Ali, Amal& Darwish, Ayman& Ali, Fatimah& Ibrahim, Muhammad& Hamdi, Lamya. 2015. Validity of magnetic resonance image and HLA-B27 in early detection of sacroiliitis in Egyptian spondyloarthropathic patients. Egyptian Rheumatology and Rehabilitation،Vol. 42, no. 3, pp.137-144.
https://search.emarefa.net/detail/BIM-629038
Modern Language Association (MLA)
al-Sharif, Ruhiyah R.…[et al.]. Validity of magnetic resonance image and HLA-B27 in early detection of sacroiliitis in Egyptian spondyloarthropathic patients. Egyptian Rheumatology and Rehabilitation Vol. 42, no. 3 (Sep. 2015), pp.137-144.
https://search.emarefa.net/detail/BIM-629038
American Medical Association (AMA)
al-Sharif, Ruhiyah R.& Ali, Amal& Darwish, Ayman& Ali, Fatimah& Ibrahim, Muhammad& Hamdi, Lamya. Validity of magnetic resonance image and HLA-B27 in early detection of sacroiliitis in Egyptian spondyloarthropathic patients. Egyptian Rheumatology and Rehabilitation. 2015. Vol. 42, no. 3, pp.137-144.
https://search.emarefa.net/detail/BIM-629038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 143-144
Record ID
BIM-629038