Association of dialysis adequacy with nutritional and inflammatory status in patients with chronic kidney failure
Joint Authors
Himayati, Ruya
Lesanpezeshki, Mahbub
Sayfi, Zubaydah
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 6 (31 Dec. 2015), pp.1154-1160, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
The number of patients with dialysis-dependent renal failure has increased in the past years worldwide.
Several parameters have been introduced for the quantitative assessment of dialysis adequacy.
The National Cooperative Dialysis Study results indicated that Kt/V and timeaveraged concentration of urea (TAC) are predictors of mortality in patients who receive maintenance hemodialysis (HD).
Also, the protein catabolic ratio (PCR), which is an indicator of nutritional status, can predict patients’ mortality.
Our aim was to assess the impact of parameters that show dialysis adequacy on indices of nutrition or inflammation.
A total of 46 patients were included in the study; eight patients were excluded during the course of the study and 38 patients were enrolled in the final analysis.
All patients were receiving HD for at least for three months.
HD was administered three times per week and the study lasted for two months.
Kt/V, TAC and PCR were assessed at the beginning of the study based on patients' urea and blood urea nitrogen in the first week of our study; these calculations were repeated at the end of the first and second months using the mean of the mentioned values in the month.
Both adequacy indices significantly and positively correlated with changes in PCR (P < 0.001).
However, no significant correlation was detectable between Kt/V and TAC with either body mass index and albumin or C-reactive protein.
Based on the Kt/V values, patients with adequate dialysis had slower decrease in the PCR (P < 0.001).
Our results indicate that adequacy of dialysis is correlated with patients’ nutritional status.
No correlation was observed between dialysis adequacy and inflammatory status.
American Psychological Association (APA)
Himayati, Ruya& Lesanpezeshki, Mahbub& Sayfi, Zubaydah. 2015. Association of dialysis adequacy with nutritional and inflammatory status in patients with chronic kidney failure. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 6, pp.1154-1160.
https://search.emarefa.net/detail/BIM-629541
Modern Language Association (MLA)
Himayati, Ruya…[et al.]. Association of dialysis adequacy with nutritional and inflammatory status in patients with chronic kidney failure. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 6 (Nov. / Dec. 2015), pp.1154-1160.
https://search.emarefa.net/detail/BIM-629541
American Medical Association (AMA)
Himayati, Ruya& Lesanpezeshki, Mahbub& Sayfi, Zubaydah. Association of dialysis adequacy with nutritional and inflammatory status in patients with chronic kidney failure. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 6, pp.1154-1160.
https://search.emarefa.net/detail/BIM-629541
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1159-1160
Record ID
BIM-629541