Morbidity and mortality associated with Plasmodium vivax and Plasmodium falciparum infection in a tertiary care kidney hospital
Joint Authors
Druhlia, Murtaza F.
Husayn, Mhaywash
Imtiaz, Salman
Ahmad, Asim
Nasir, Kiran
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 26, Issue 6 (31 Dec. 2015), pp.1169-1176, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2015-12-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
Malaria is a disease of tropical regions and both types of plasmodia, i.e.
Plasmodium falciparum and Plasmodium vivax, cause significant morbidity and mortality.
P.
vivax was thought to be benign and cause less morbidity and mortality.
Many reports showed the devastating effect of vivax malaria too.
We compared the clinical symptoms, laboratory markers, treatment and outcome of both the plasmodia.
This is a retrospective analysis of 95 patients admitted to The Kidney Center, Karachi in a duration of 15 years (1997–2012); 45 patients with falciparum malaria and 50 patients with vivax malaria, and compared the clinical presentation, laboratory workup, treatment and outcome in both groups.
The two groups constitute a mixed population of diabetes, chronic kidney disease (CKD) and hemodialysis patients.
Both plasmodia have an equal clinical impact in terms of fever and rigors, anorexia, nausea, feeling of dyspnea, change in the mental status, changes in the urine color, diarrhea, volume depletion and pedal edema.
However, patients with falciparum had significantly more vomiting (P = 0.02), oliguria (P = 0.003) and jaundice (P = 0.003).
Laboratory parameters also showed a severe impact of falciparum, as there was more severe anemia and kidney and liver dysfunction.
More patients were treated with dialysis and blood transfusion in the falciparum group.
The outcome in the two groups was not significantly different in terms of death and days of hospitalization.
Falciparum malaria has a higher clinical impact than the vivax malaria, but vivax is not as benign as it was once thought to be.
It also has devastating effects on vulnerable populations like patients with CKD and diabetes.
American Psychological Association (APA)
Imtiaz, Salman& Druhlia, Murtaza F.& Nasir, Kiran& Husayn, Mhaywash& Ahmad, Asim. 2015. Morbidity and mortality associated with Plasmodium vivax and Plasmodium falciparum infection in a tertiary care kidney hospital. Saudi Journal of Kidney Diseases and Transplantation،Vol. 26, no. 6, pp.1169-1176.
https://search.emarefa.net/detail/BIM-629605
Modern Language Association (MLA)
Imtiaz, Salman…[et al.]. Morbidity and mortality associated with Plasmodium vivax and Plasmodium falciparum infection in a tertiary care kidney hospital. Saudi Journal of Kidney Diseases and Transplantation Vol. 26, no. 6 (Nov. / Dec. 2015), pp.1169-1176.
https://search.emarefa.net/detail/BIM-629605
American Medical Association (AMA)
Imtiaz, Salman& Druhlia, Murtaza F.& Nasir, Kiran& Husayn, Mhaywash& Ahmad, Asim. Morbidity and mortality associated with Plasmodium vivax and Plasmodium falciparum infection in a tertiary care kidney hospital. Saudi Journal of Kidney Diseases and Transplantation. 2015. Vol. 26, no. 6, pp.1169-1176.
https://search.emarefa.net/detail/BIM-629605
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1175-1176
Record ID
BIM-629605