Profile of acute kidney injury after open heart surgeries in a tertiary care hospital

Abstract EN

Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery.

A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, etiology and outcome.

Post-operative AKI was considered when the post-operative serum creatinine was >1.5 mg / dL or there was doubling of serum creatinine above the baseline (pre-operative) with a prior normal renal function.

The incidence of AKI in the post-operative period in our study was 17.7 %.

The common etiological factors for AKI in our study were sepsis, hypotension, prolonged need for ventilator and inotropic support and drugs given in the post-operative period.

The important risk factors for the development of AKI in the post-operative period were hypertension, diabetes mellitus, gout, prolonged total bypass time and prolonged aortic cross–clamp time.

The overall mortality in our study subjects was 11.3 % (seven of 62 died) and the mortality in the patients who developed post-operative AKI was 71.4 %.