Living unrelated renal transplant : outcome and issues
Joint Authors
al-Jamal, Hazim
Allam, Awatif A.
al-Wakil, Jamal S.
Tarif, Numan
Kechrid, Muhammad
Mutawalli, Ahmad Hassan
Malik, Ghulam Hasan
al-Mohaya, Sulayman
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 11, Issue 4 (31 Aug. 2000)7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2000-08-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
Living unrelated transplantation (LURT) is emerging as a practical option in renal transplantation due to shortage of living related and cadaver donors.
We report a six-years (December 1991 to December 1996) follow-up of 60 LURT patients.
The majority of these patients (95 %) were transplanted outside the Kingdom of Saudi Arabia ; 37 in India, 14 in Egypt, five in the USA and one in Pakistan.
Only three patients (emotionally related) were transplanted in Saudi Arabia.
Before transplantation, 50 (83.4 %) patients were on chronic hemodialysis, three (5 %) on peritoneal dialysis and three (5 %) were transplanted pre-emptively.
Post-operatively, the majority of the study patients were on three drug immunosuppressive therapy.
One and five year graft survival was 93.0 % and 59.6 %, while patient survival at one and three years was 93.7 % and 81 %, respectively.
Surgical complications included lymphocele in 10 % of the study patients, urinary leak in 8.3 %, and bleeding from the vascular anastomosis in 6.6 %.
There were eight episodes of acute rejection in eight (13.3 %) patients and all episodes were successfully treated ; two patients required monoclonal anti-lymphocyte antibodies (OKT3).
Eleven (18.3 %) patients developed chronic rejection, which resulted in the loss of ten (90 %) allografts.
Infection was the commonest cause for hospital admission ; urinary tract infection (UTI) being responsible for 40 % of admissions.
Three patients had Cytomegalovirus pneumonia, one had Pneumocystis Carinii pneumonia and one had candida pneumonia.
Two (3 %) patients developed Kaposi's sarcoma.
We conclude that LURT can help in overcoming the shortage of organs for transplant, however, commercial transplantion in developing countries is associated with high morbidity and mortality.
American Psychological Association (APA)
al-Wakil, Jamal S.& Mutawalli, Ahmad Hassan& Tarif, Numan& Malik, Ghulam Hasan& al-Mohaya, Sulayman& Allam, Awatif A.…[et al.]. 2000. Living unrelated renal transplant : outcome and issues. Saudi Journal of Kidney Diseases and Transplantation،Vol. 11, no. 4.
https://search.emarefa.net/detail/BIM-62981
Modern Language Association (MLA)
al-Wakil, Jamal S.…[et al.]. Living unrelated renal transplant : outcome and issues. Saudi Journal of Kidney Diseases and Transplantation Vol. 11, no. 4 (Dec. 2000).
https://search.emarefa.net/detail/BIM-62981
American Medical Association (AMA)
al-Wakil, Jamal S.& Mutawalli, Ahmad Hassan& Tarif, Numan& Malik, Ghulam Hasan& al-Mohaya, Sulayman& Allam, Awatif A.…[et al.]. Living unrelated renal transplant : outcome and issues. Saudi Journal of Kidney Diseases and Transplantation. 2000. Vol. 11, no. 4.
https://search.emarefa.net/detail/BIM-62981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-62981