Glomerulonephritis in Saudi Arabia : a review
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 11, Issue 4 (31 Aug. 2000)10 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2000-08-31
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Topics
Abstract EN
Glomerulonephritis (GN) is one of the leading causes of end-stage renal disease.
A good understanding of its pattern and prevalence as well as exploration of effective therapeutic strategies for protecting the glomerulus, would have tremendous impact on public health.
In the Kingdom of Saudi Arabia (KSA), focal and segmental glomerulo sclerosis (FSGS) is the commonest type of primary glomerular diseases (PGD) encountered in clinical practice.
Its prevalence varies from less than 4 % in Gizan, in the southern part of KSA, to approximately 35 % in Riyadh, central Saudi Arabia.
In our experience, the nephrotic syndrome was the commonest mode of presentation of FSGS.
Response to corticosteroid therapy is generally poor and the mortality rate is high.
Mesangioproliferative GN is the second most common GN constituting up to 25 % of PGD in our experience.
Other researchers from different parts of the Kingdom, however, have given prevalence rates ranging from 8 to 57.1 %.
The reported prevalence of Immunoglobulin-A nephropathy (IgAN) in KSA ranges from 5.8 % to 13.6 %.
It is more common in the elderly, and men are affected more often than women.
In contrast to KSA, IgAN is the commonest PGD in Japan, China, Hong Kong, Singapore and Taiwan.
Membranous GN (MGN) is less common in KSA than encountered elsewhere, the prevalence ranging from 3.9 to 21.8 %.
Nephropathy secondary to systemic diseases are also common in KSA.
Lupus nephritis (LN) accounted for 48.5 % of secondary glomerular diseases (SGD) with the combination of WHO classes III and IV (aggressive types of LN) accounting for 56 % of all patients.
LN is another disease where differences in racial susceptibility may account for the uneven distribution.
Post-streptococcal GN seems to be declining in frequency in KSA, the reported prevalence ranging from 2.7 % to 2.9 %.
American Psychological Association (APA)
Mutawalli, Ahmad Hassan. 2000. Glomerulonephritis in Saudi Arabia : a review. Saudi Journal of Kidney Diseases and Transplantation،Vol. 11, no. 4.
https://search.emarefa.net/detail/BIM-63026
Modern Language Association (MLA)
Mutawalli, Ahmad Hassan. Glomerulonephritis in Saudi Arabia : a review. Saudi Journal of Kidney Diseases and Transplantation Vol. 11, no. 4 (Dec. 2000).
https://search.emarefa.net/detail/BIM-63026
American Medical Association (AMA)
Mutawalli, Ahmad Hassan. Glomerulonephritis in Saudi Arabia : a review. Saudi Journal of Kidney Diseases and Transplantation. 2000. Vol. 11, no. 4.
https://search.emarefa.net/detail/BIM-63026
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-63026