![](/images/graphics-bg.png)
The efficacy of hepatitis b vaccination among school age children in southern Iran
Joint Authors
Lankarani, K. B.
Moghadami, M.
al-Borzi, A.
Mahbudi, A.
Hashimi, S. A.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 12, Issue 1 (30 Oct. 2010), pp.45-48, 4 p.
Publisher
Publication Date
2010-10-30
Country of Publication
United Arab Emirates
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background : primary prevention by vaccination to increase herd immunity remains the main thrust in the control of hepatitis B virus (HBV) infection and many countries such as Islamic Republic of Iran have incorporated HBV vaccination into their national expanded program of immunization.
This study was performed to determine the vaccine efficacy of hepatitis B infection between vaccinated and non-vaccinated school-aged children.
Methods : three hundred and ninety four students aged 6 to 8 years who received the hepatitis vaccine in the infancy and 314 students aged 9 to 10 years who did not receive it in Sepidan, southern Iran were enrolled.
We also determined the titer of anti HBs Ab in the vaccinated students.
Results : Two students (0.5%) were HBV infected (positive HBC Ab) and none were a chronic carrier.
Two hundred and forty nine students (63.2%) had anti HBs titer greater than 10 IU / ml.
One hundred and seventeen students (30%) had anti HBs titer between 1 and 10 IU / ml and only 28 children had anti HBs titer less than 1 IU / ml.
Five (1.6%) were HBV infected (positive HBc Ab) and 2 (0.6%) were chronic carriers (positive HBs Ag).
The efficacy of the vaccine 6-8 years after vaccination was 67.9% (95 CI 78-92).
Conclusion : our results showed that similar to other studies, vaccination could not reduce the infection rate but had a significant effect on the reduction of chronic infection and carrier state, emphasizing on the role of vaccination in the control of HBV infection in an endemic region.
American Psychological Association (APA)
Hashimi, S. A.& Moghadami, M.& Lankarani, K. B.& al-Borzi, A.& Mahbudi, A.. 2010. The efficacy of hepatitis b vaccination among school age children in southern Iran. Iranian Red Crescent Medical Journal،Vol. 12, no. 1, pp.45-48.
https://search.emarefa.net/detail/BIM-63040
Modern Language Association (MLA)
Mahbudi, A.…[et al.]. The efficacy of hepatitis b vaccination among school age children in southern Iran. Iranian Red Crescent Medical Journal Vol. 12, no. 1 (Oct. 2010), pp.45-48.
https://search.emarefa.net/detail/BIM-63040
American Medical Association (AMA)
Hashimi, S. A.& Moghadami, M.& Lankarani, K. B.& al-Borzi, A.& Mahbudi, A.. The efficacy of hepatitis b vaccination among school age children in southern Iran. Iranian Red Crescent Medical Journal. 2010. Vol. 12, no. 1, pp.45-48.
https://search.emarefa.net/detail/BIM-63040
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 48
Record ID
BIM-63040