The long-term results of pediatric patients with primary focal and segmental glomerulosclerosis
Joint Authors
Sozeri, Betul
Mir, Sivgi
Mutlubas, Fatimah
Sen, Sait
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 1 (28 Feb. 2010), pp.87-92, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-02-28
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Focal and segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroidresistant nephrotic syndrome (SRNS) and end-stage renal disease (ESRD).
In this retrospective study, we report on 34 pediatric patients with FSGS who were diagnosed and treated from 1992 to 2006.
The mean age at onset was 6.3 ± 4.3 years.
All patients had nephrotic-range proteinuria.
Microscopic hematuria was seen in three patients and hypertension was seen in 15 patients at presentation.
All patients were treated with steroids (oral and/or methylprednisolone), while 23 patients received cytotoxic therapy in addition.
The mean follow-up period was 8.6 ± 3.3 years at the end of which, 59% of patients achieved complete or partial remission, 20.5% continued to have active renal disease while 20.5% of the patients developed CKD.
Our study suggests that most of the patients with FSGS progress to renal insufficiency.
Steroid therapy increases the chances of remission and preserves renal function in patients with sporadic primary FSGS
American Psychological Association (APA)
Sozeri, Betul& Mir, Sivgi& Mutlubas, Fatimah& Sen, Sait. 2010. The long-term results of pediatric patients with primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 1, pp.87-92.
https://search.emarefa.net/detail/BIM-63424
Modern Language Association (MLA)
Mir, Sivgi…[et al.]. The long-term results of pediatric patients with primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 1 (Feb. 2010), pp.87-92.
https://search.emarefa.net/detail/BIM-63424
American Medical Association (AMA)
Sozeri, Betul& Mir, Sivgi& Mutlubas, Fatimah& Sen, Sait. The long-term results of pediatric patients with primary focal and segmental glomerulosclerosis. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 1, pp.87-92.
https://search.emarefa.net/detail/BIM-63424
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : pp. 87-92.
Record ID
BIM-63424