Response to rituximab in a refractory case of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus
Joint Authors
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 1 (28 Feb. 2010), pp.109-112, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-02-28
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
- Diseases
- Therapeutics
- Skin
- Complications(Medicine)
- Lupus erythematosus
- Thrombotic microangiopathy
- Rituximab
Abstract EN
Thrombotic thrombocytopenic purpura (TTP) is a serious disorder with a significant morbidity and mortality.
Majority of cases of TTP are idiopathic, but some cases may be secondary to connective tissue diseases.
TTP has been rarely associated with systemic lupus erythematosus (SLE) and may be refractory to treatment with plasma exchange, requiring immunosuppressive therapy.
We describe a patient with TTP and SLE who was refractory to plasma exchange and corticosteroids but responded to anti-CD20 antibody rituximab with continued remission after eight months of follow-up.
Rituximab appears to be an effective treatment in refractory cases of TTP associated with SLE.
American Psychological Association (APA)
Niaz, Faraz Azim& Alim, Amir. 2010. Response to rituximab in a refractory case of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 1, pp.109-112.
https://search.emarefa.net/detail/BIM-63458
Modern Language Association (MLA)
Niaz, Faraz Azim& Alim, Amir. Response to rituximab in a refractory case of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 1 (Feb. 2010), pp.109-112.
https://search.emarefa.net/detail/BIM-63458
American Medical Association (AMA)
Niaz, Faraz Azim& Alim, Amir. Response to rituximab in a refractory case of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 1, pp.109-112.
https://search.emarefa.net/detail/BIM-63458
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 112.
Record ID
BIM-63458