Impact of cardiovascular risk factors on the outcome of renal transplantation
Joint Authors
Moghimi, Mehrdad
Falaknazi, Kianoosh
Bagheri, Nazila
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 3 (30 Jun. 2010), pp.438-442, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-06-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Cardiovascular diseases are common in renal transplant recipients and renal insufficiency has been shown to be a risk factor for cardiovascular disease.
Some studies have reported that cardiovascular risk factors may contribute to the outcome of renal transplantation.
This study was performed to determine the impact of cardiovascular risk factors on the outcome of renal transplantation in Iranian subjects.
This is a retrospective, observational study including patients of 20-85 years of age who had undergone renal transplantation.
Parameters documented and analyzed included demographics, cardiovascular risk factors, past medical history, date of last transplantation, the outcome of transplant, last measured serum creatinine, and cause of graft failure, rejection, and death.
A total of 192 patients were analyzed including 152 in the case group (with identifiable cardiovascular risk factors) and 40 controls (transplant recipients without identifiable risk factors).
The mean serum creatinine in the case and control groups were 1.33 ± 0.13 and 1.29 ± 0.36 mg / dL respectively (P = 0.493).
Response to transplantation was categorized based on a report from the World Health Organization.
Complete response to grafting occurred in the control group more than the case group (P = 0.009), while frequency of partial response to grafting was higher in the case group (0.008).
A history of chronic obstructive pulmonary diseases (COPD) could significantly predict the outcome of grafting (P = 0.008) as could the occurrence of renal failure (P = 0.022).
Results were consistently reproduced using multivariate cumulative log it model.
Our study indicates that the measured cardiovascular risk factors do not significantly influence the outcome of renal transplantation.
American Psychological Association (APA)
Moghimi, Mehrdad& Falaknazi, Kianoosh& Bagheri, Nazila. 2010. Impact of cardiovascular risk factors on the outcome of renal transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 3, pp.438-442.
https://search.emarefa.net/detail/BIM-63573
Modern Language Association (MLA)
Moghimi, Mehrdad…[et al.]. Impact of cardiovascular risk factors on the outcome of renal transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 3 (Jun. 2010), pp.438-442.
https://search.emarefa.net/detail/BIM-63573
American Medical Association (AMA)
Moghimi, Mehrdad& Falaknazi, Kianoosh& Bagheri, Nazila. Impact of cardiovascular risk factors on the outcome of renal transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 3, pp.438-442.
https://search.emarefa.net/detail/BIM-63573
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 441-442
Record ID
BIM-63573