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The role of oral L-carnitine therapy in chronic hemodialysis patients
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 3 (30 Jun. 2010), pp.454-459, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-06-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
To evaluate the effects of L-carnitine oral supplementation on anemia and cardiac function in patients on maintenance hemodialysis (HD), we studied 55 adult chronic HD patients at our center during the period from January 2006 to June 2006 and divided them into two groups; a group of 20 patients who received 1,500 mg/day oral L-carnitine and a control group of 35 patients.
Both groups were on erythropoietin therapy.
Echogardiographic studies were performed before and at the end of the study.
The mean hemoglobin levels were comparable in the L-carnitine group and the control group at the start and after 6 months of therapy (8.63 ± 1.77 and 9.39 ± 2.02 gm/dL, P= 0.18; 10.49 ± 1.65 and 10.92 ± 2.48 gm/dL, P= 0.76, respectively).
The mean weekly maintenance dose of erythropoietin was not statistically significantly different in Lcarnitine group (80.16 ± 35.61 units/kg) and the control group (91.9 ± 38.21 units/kg, P= 0.20).
In addition no significant improvement could be observed in the echogardiographic findings in the L-carnitine group after therapy.
We conclude that our study revealed no significant improvement in hemoglobin, erythropoietin dose and echocardiographic findings after six months of therapy.
Long-term studies including larger number of patients are required to clarify the questionable role of L-carnitine in the HD patients.
American Psychological Association (APA)
Sabri, Ala A.. 2010. The role of oral L-carnitine therapy in chronic hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 3, pp.454-459.
https://search.emarefa.net/detail/BIM-63579
Modern Language Association (MLA)
Sabri, Ala A.. The role of oral L-carnitine therapy in chronic hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 3 (Jun. 2010), pp.454-459.
https://search.emarefa.net/detail/BIM-63579
American Medical Association (AMA)
Sabri, Ala A.. The role of oral L-carnitine therapy in chronic hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 3, pp.454-459.
https://search.emarefa.net/detail/BIM-63579
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 458-459
Record ID
BIM-63579