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Systolic function and intraventricular mechanical dyssynchrony assessed by advanced speckle tracking imaging with n-terminal prohormone of brain natriuretic peptide for outcome prediction in chronic heart failure patients
Other Title(s)
الوظيفة الانقباضية وخلل التزامن الميكانيكي داخل البطين متابعة بتقنية التنقيط بالموجات الصوتية للقلب مع بروهرمون ناتيروتك ببتايد للتنبؤ بالنتائج لمرضى فشل القلب المزمن
Joint Authors
Ubayd, Fadiyah
Abd al-Wahid, Fadilah
Maskon, Oteh
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 13, Issue 4 (30 Nov. 2013), pp.551-559, 9 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2013-11-30
Country of Publication
Oman
No. of Pages
9
Main Subjects
Abstract EN
The aim of this study was to assess longitudinal systolic function and mechanical synchrony parameters derived from advanced speckle tracking echocardiography (STE) and to determine their correlation with N-terminal prohormone of brain natriuretic peptide (NT-proBNP).
Their influence on heart failure (HF) outcomes at a one-year follow-up, not clarified in previous studies, was also examined.
Methods: Advanced STE was performed from August 2009 to January 2012 in 103 chronic HF patients at the University Kebangsaan Malaysia Medical Center to assess their longitudinal systolic function and synchrony parameters; NT-proBNP blood measurement was taken at the same time.
Results: Longitudinal cardiac velocity; strain; strain rate; displacement; intraventricular mechanical dyssynchrony based on the standard deviation (SD) of time to peak systolic strain rate (Tsr-SD); displacement, and antero-septal to posterior (AS-P) delay were associated with cardiac events.
In multivariate analysis, NT-proBNP and AS-P delay were identified as independent predictors for cardiac events.
Significant correlations were found between NT-proBNP and longitudinal velocity; displacement; strain; strain rate, and ejection fraction.
Log NT-proBNP levels correlated moderately with the SD of time to peak displacement and to peak strain, and there was a small correlation with maximal differences and SD of time to peak velocity.
A multiple linear analysis revealed that NT-proBNP levels significantly correlated to age, ejection fraction and velocity.
Conclusion: Advanced STE is a promising technique which accelerates the clinical application of the quantification of myocardial function and synchrony.
STE parameters and NT-proBNP have the ability to identify patients at higher risk of death and hospitalisation.
American Psychological Association (APA)
Ubayd, Fadiyah& Maskon, Oteh& Abd al-Wahid, Fadilah. 2013. Systolic function and intraventricular mechanical dyssynchrony assessed by advanced speckle tracking imaging with n-terminal prohormone of brain natriuretic peptide for outcome prediction in chronic heart failure patients. Sultan Qaboos University Medical Journal،Vol. 13, no. 4, pp.551-559.
https://search.emarefa.net/detail/BIM-642385
Modern Language Association (MLA)
Ubayd, Fadiyah…[et al.]. Systolic function and intraventricular mechanical dyssynchrony assessed by advanced speckle tracking imaging with n-terminal prohormone of brain natriuretic peptide for outcome prediction in chronic heart failure patients. Sultan Qaboos University Medical Journal Vol. 13, no. 4 (Nov. 2013), pp.551-559.
https://search.emarefa.net/detail/BIM-642385
American Medical Association (AMA)
Ubayd, Fadiyah& Maskon, Oteh& Abd al-Wahid, Fadilah. Systolic function and intraventricular mechanical dyssynchrony assessed by advanced speckle tracking imaging with n-terminal prohormone of brain natriuretic peptide for outcome prediction in chronic heart failure patients. Sultan Qaboos University Medical Journal. 2013. Vol. 13, no. 4, pp.551-559.
https://search.emarefa.net/detail/BIM-642385
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 558-559
Record ID
BIM-642385