Donor specific anti-hla antibodies detection and impact in kidney transplantation
Joint Authors
Mourani, Chebl
Azar, Hibah
Moukarzel, Maroun
Shilala, Danya Nimah
Source
Issue
Vol. 63, Issue 3 (30 Sep. 2015), pp.154-158, 5 p.
Publisher
Publication Date
2015-09-30
Country of Publication
Lebanon
No. of Pages
5
Main Subjects
Topics
Abstract EN
Kidney transplantation is now accepted to be the best treatment for end-stage renal disease.
Despite the improvement of immunosuppressive therapy, there is still actually substantial loss of allografts, in part due to uncontrolled humoral immunity.
For many years, the primary technique for the detection of anti-HLA antibodies was the CDC (complement dependent cytotoxicity).
The recent use of solid phase assays, mainly the Luminex technology allowed detection of antibodies at much lower levels, and it has been shown that these antibodies have negative impact on the graft survival.
We herein review the principal techniques for anti-HLA detection and the different presentations of humoral rejection.
American Psychological Association (APA)
Azar, Hibah& Mourani, Chebl& Shilala, Danya Nimah& Moukarzel, Maroun. 2015. Donor specific anti-hla antibodies detection and impact in kidney transplantation. Journal Médical Libanais،Vol. 63, no. 3, pp.154-158.
https://search.emarefa.net/detail/BIM-645042
Modern Language Association (MLA)
Azar, Hibah…[et al.]. Donor specific anti-hla antibodies detection and impact in kidney transplantation. Journal Médical Libanais Vol. 63, no. 3 (2015), pp.154-158.
https://search.emarefa.net/detail/BIM-645042
American Medical Association (AMA)
Azar, Hibah& Mourani, Chebl& Shilala, Danya Nimah& Moukarzel, Maroun. Donor specific anti-hla antibodies detection and impact in kidney transplantation. Journal Médical Libanais. 2015. Vol. 63, no. 3, pp.154-158.
https://search.emarefa.net/detail/BIM-645042
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 157-158
Record ID
BIM-645042