Evaluation of the optimum preemptive dose of gabapentin and its postoperative morphine-sparing effect after debridement of burned patient
Joint Authors
al-Azzazi, Hisham
Ata Allah, Rafiq
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 7, Issue 2 (30 Jun. 2014), pp.138-142, 5 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2014-06-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
We evaluated the optimal dose of preemptive gabapentin for postoperative pain relief after debridement of burned patient and its effect on morphine consumption during the initial 24 h after surgery.
Patients were divided into seven groups to receive gabapentin 300, 600, 900, 1200, 1500, 1800, and 2100 mg 1 h before surgery.
After surgery, patients were transferred to the postanesthesia care unit.
Pain scores were recorded at time points of 2, 6, 12, 18, and 24 h in postanesthesia care unit on a visual analog scale (VAS: 0–10 cm).
Patients received patient-controlled analgesia (morphine), and total morphine consumption during the initial 24 h was recorded.
Data were entered into statistical software package SPSS 9.0 for analysis.
Patients who received gabapentin 600, 900, 1200, 1500, and 1800 mg had lower VAS scores at all time points than patients who received gabapentin 300 mg.
Increasing the dose of gabapentin from 1500 to 1800 mg did not decrease the VAS score nor it decreased morphine consumption.
Thus, gabapentin 1500 mg is the optimal preemptive dose for postoperative pain relief following debridement of burn patients.
American Psychological Association (APA)
al-Azzazi, Hisham& Ata Allah, Rafiq. 2014. Evaluation of the optimum preemptive dose of gabapentin and its postoperative morphine-sparing effect after debridement of burned patient. Ain Shams Journal of Anesthesiology،Vol. 7, no. 2, pp.138-142.
https://search.emarefa.net/detail/BIM-649104
Modern Language Association (MLA)
al-Azzazi, Hisham& Ata Allah, Rafiq. Evaluation of the optimum preemptive dose of gabapentin and its postoperative morphine-sparing effect after debridement of burned patient. Ain Shams Journal of Anesthesiology Vol. 7, no. 2 (Apr. / Jun. 2014), pp.138-142.
https://search.emarefa.net/detail/BIM-649104
American Medical Association (AMA)
al-Azzazi, Hisham& Ata Allah, Rafiq. Evaluation of the optimum preemptive dose of gabapentin and its postoperative morphine-sparing effect after debridement of burned patient. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 2, pp.138-142.
https://search.emarefa.net/detail/BIM-649104
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 142
Record ID
BIM-649104