Catastrophic calciphylaxis in a patient with lupus nephritis and recent onset of end-stage renal disease
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 21, Issue 2 (28 Apr. 2010), pp.323-327, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2010-04-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
- Kidneys
- Diseases
- Chronic diseases
- Complications(Medicine)
- Kidney failure
- Calciphylaxis
- Calcification
- Catastrophic illness
- Lupus nephritis
Abstract EN
Painful violaceous skin lesions that progress to non-healing ulceration and gangrene characterize calciphylaxis.
These lesions are associated with secondary hyperparathyroidism and generally occur in patients on dialysis for more than one year.
Hyperphosphatemia and hypoalbuminemia are the major risk factors for calciphylaxis.
It is usually resistant to medical treatment although parathyroidectomy can help in controlling the disease.
The mortality rate of calciphylaxis is very high due to uncontrollable sepsis.
In our case, a young female with systemic lupus erythematosus (SLE) developed calciphylaxis within a short period after the onset of hemodialysis; she had a short period of hyperphosphatemia prior to dialysis.
The serum phosphate was 4.24 mmol/L, calcium was 1.66 mmol/L, parathormone was 38 and calcium-phosphate was 7.0 mmol/L.
It is likely that SLE provoked the development of calciphylaxis.
The patient was treated medically but unfortunately died secondary to sepsis
American Psychological Association (APA)
al-Biladi, Fatimah I.. 2010. Catastrophic calciphylaxis in a patient with lupus nephritis and recent onset of end-stage renal disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 21, no. 2, pp.323-327.
https://search.emarefa.net/detail/BIM-64921
Modern Language Association (MLA)
al-Biladi, Fatimah I.. Catastrophic calciphylaxis in a patient with lupus nephritis and recent onset of end-stage renal disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 21, no. 2 (Apr. 2010), pp.323-327.
https://search.emarefa.net/detail/BIM-64921
American Medical Association (AMA)
al-Biladi, Fatimah I.. Catastrophic calciphylaxis in a patient with lupus nephritis and recent onset of end-stage renal disease. Saudi Journal of Kidney Diseases and Transplantation. 2010. Vol. 21, no. 2, pp.323-327.
https://search.emarefa.net/detail/BIM-64921
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 326-327.
Record ID
BIM-64921