Addition of dexmedetomidine to bupivacaine in the lumbar plexus block potentiates postoperative analgesia among hip arthroplasty patients : a prospective randomized controlled trial
Author
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 8, Issue 2 (30 Jun. 2015), pp.269-275, 7 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2015-06-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background Dexmedetomidine is an α2-adrenergic agonist, which prolongs analgesia when administered in neuroaxial and peripheral nerve blocks.
The aim of this study was to evaluate the effect of adding dexmedetomidine to bupivacaine in the lumbar plexus block (LPB) as regards analgesic characteristics and opioid consumption.
Materials and methods Fifty patients scheduled for total hip arthroplasty were divided into two groups: group B patients (N = 25) received LPB with 30 ml of 0.25% bupivacaine and 2 ml of normal saline, while group BD patients (N = 25) received LPB with 30 ml of 0.25% bupivacaine and dexmedetomidine 1 μg/kg diluted in 2 ml of normal saline.
Time for fi rst analgesic administration, totally used doses of morphine, pain scores, hemodynamic data, and side effects were recorded.
Results Demographic and operative characteristics were comparable between the two groups.
The time for fi rst analgesic request was longer in group BD than group B [502 vs.
243 min (P < 0.001) and the total morphine consumption in 24 h was less among group BD patients compared with those in group B (19 vs.
32 mg, P < 0.001)].
The visual analogue score was signifi cantly lower in group BD in the fi rst 8 h postoperatively compared with group B (P < 0.001).
In group BD a lower heart rate was noticed 120 min postinduction that continued for the fi rst 4 h postoperatively (P < 0.001).
Conclusion The addition of dexmedetomidine to bupivacaine in LPB prolongs the time for fi rst analgesic requirement and reduces the total postoperative opioid consumption without major side effects.
American Psychological Association (APA)
Sulayman, Hisham F.. 2015. Addition of dexmedetomidine to bupivacaine in the lumbar plexus block potentiates postoperative analgesia among hip arthroplasty patients : a prospective randomized controlled trial. Ain Shams Journal of Anesthesiology،Vol. 8, no. 2, pp.269-275.
https://search.emarefa.net/detail/BIM-650305
Modern Language Association (MLA)
Sulayman, Hisham F.. Addition of dexmedetomidine to bupivacaine in the lumbar plexus block potentiates postoperative analgesia among hip arthroplasty patients : a prospective randomized controlled trial. Ain Shams Journal of Anesthesiology Vol. 8, no. 2 (Apr. / Jun. 2015), pp.269-275.
https://search.emarefa.net/detail/BIM-650305
American Medical Association (AMA)
Sulayman, Hisham F.. Addition of dexmedetomidine to bupivacaine in the lumbar plexus block potentiates postoperative analgesia among hip arthroplasty patients : a prospective randomized controlled trial. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 2, pp.269-275.
https://search.emarefa.net/detail/BIM-650305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 275
Record ID
BIM-650305