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Validity of right ventricular end-diastolic volume as a guide for fluid resuscitation compared with central venous pressure in living donor liver transplantation recipients : a randomized controlled trial
Joint Authors
al-Murshidi, Muhammad
Salah, Tariq
Yasin, Amr M.
al-Sarraf, Walid R.
Sultan, Ahmad Muhammad
al-Sadani, Muhammad
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 7, Issue 1 (30 Apr. 2014), pp.19-24, 6 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2014-04-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background Fluid transfusion inflects major impact on graft and renal functions in living donor liver transplantation.
Major hemodynamic swinging renders intraoperative preload assessment crucial yet difficult task.
In this prospective randomized double-blind controlled trial, we examined the validity of right ventricular end-diastolic volume (RVEDV) as a preload indicator compared with central venous pressure (CVP) in recipients of living donor liver grafts.
Patients and methods A total of 21 patients included in the study were randomly allocated into either the RVEDV group (n = 11) or the CVP group (n = 10) on the basis of the trigger for operative fluid resuscitation.
Basal value for both right ventricular end-diastolic volume index (RVEDVI) and CVP was recorded after laparotomy.
Fluids (albumin 4% or Voluven) were given in boluses of 250 ml when the triggering parameter decreased by 20% of its basal value.
Hemodynamic data were recorded after laparotomy (basal), at the end of hepatectomy, before portal unclamping, 15 min after portal unclamping, and at skin closure.
Total fluids infused, blood loss, early graft, and patient’s outcomes were also recorded.
Results Both groups were similar with respect to demographic and operative data.
Fluids infused were significantly higher in the RVEDVI group compared with the CVP group.
Cardiac output and stroke volume were significantly higher in the RVEDVI than in the CVP group starting at end of hepatectomy and thereafter.
Urine output was significantly less in the CVP group compared with the RVEDVI group.
Hypotensive episodes were greater in the CVP group compared with the RVEDVI group.
RVEDVI and CVP did not correlate at any time point.
No intergroup differences were observed with respect to early graft functions, serum creatinine, blood urea, ICU stay, 28th day graft, and patient survival.
Conclusion RVEDV appears to be a more sensitive preload indicator and a trigger for fluid resuscitation compared with CVP; however, patient monitoring with either parameter did not significantly affect the patient outcome.
American Psychological Association (APA)
Yasin, Amr M.& al-Sarraf, Walid R.& al-Murshidi, Muhammad& al-Sadani, Muhammad& Salah, Tariq& Sultan, Ahmad Muhammad. 2014. Validity of right ventricular end-diastolic volume as a guide for fluid resuscitation compared with central venous pressure in living donor liver transplantation recipients : a randomized controlled trial. Ain Shams Journal of Anesthesiology،Vol. 7, no. 1, pp.19-24.
https://search.emarefa.net/detail/BIM-650385
Modern Language Association (MLA)
Yasin, Amr M.…[et al.]. Validity of right ventricular end-diastolic volume as a guide for fluid resuscitation compared with central venous pressure in living donor liver transplantation recipients : a randomized controlled trial. Ain Shams Journal of Anesthesiology Vol. 7, no. 1 (Jan. / Apr. 2014), pp.19-24.
https://search.emarefa.net/detail/BIM-650385
American Medical Association (AMA)
Yasin, Amr M.& al-Sarraf, Walid R.& al-Murshidi, Muhammad& al-Sadani, Muhammad& Salah, Tariq& Sultan, Ahmad Muhammad. Validity of right ventricular end-diastolic volume as a guide for fluid resuscitation compared with central venous pressure in living donor liver transplantation recipients : a randomized controlled trial. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 1, pp.19-24.
https://search.emarefa.net/detail/BIM-650385
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 24
Record ID
BIM-650385