Preemptive parenteral paracetamol analgesia in off-pump coronary artery bypass
Author
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 8, Issue 1 (31 Mar. 2015), pp.21-24, 4 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2015-03-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background NSAIDs are routinely used for pain control in cardiac surgery; however, these drugs are burdened by side effects.
Paracetamol is believed to be lacking in such side effects.
The aim of this study was to examine the effi cacy of preemptive intravenous paracetamol analgesia on opioid sparing in off-pump coronary artery bypass (OPCAB).
Materials and Methods This was a prospective randomized controlled double-blinded study.
A total of 80 patients scheduled for elective OPCAB were randomly allocated into two groups: in group I (the control group) 40 patients received intravenous infusion of 100 ml of normal saline solution, whereas in group II (the paracetamol study group) 40 patients received intravenous infusion of 1 g of the study drug in 100 ml solution bag.
Solution bags were prepared by the pharmacy department, and treating teams were blinded to the infused solution until end of study.
Hemodynamic variables and sufentanil usage were recorded and compared between the two groups.
Results The two groups were comparable regarding their demographic and operative data.
Hemodynamic variables showed nonsignifi cant differences between the two studied groups.
Total intraoperative consumption of sufentanil was comparable between the two groups with insignifi cant difference.
Postoperatively, extubation time and length of ICU stay were statistically nonsignifi cant.
Conclusion Preemptive administration of parenteral paracetamol had a limited opioid-sparing effect during intraoperative management of cardiac cases undergoing OPCAB
American Psychological Association (APA)
Abd al-Salam, Khalid M. A.. 2015. Preemptive parenteral paracetamol analgesia in off-pump coronary artery bypass. Ain Shams Journal of Anesthesiology،Vol. 8, no. 1, pp.21-24.
https://search.emarefa.net/detail/BIM-650462
Modern Language Association (MLA)
Abd al-Salam, Khalid M. A.. Preemptive parenteral paracetamol analgesia in off-pump coronary artery bypass. Ain Shams Journal of Anesthesiology Vol. 8, no. 1 (Jan. / Mar. 2015), pp.21-24.
https://search.emarefa.net/detail/BIM-650462
American Medical Association (AMA)
Abd al-Salam, Khalid M. A.. Preemptive parenteral paracetamol analgesia in off-pump coronary artery bypass. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 1, pp.21-24.
https://search.emarefa.net/detail/BIM-650462
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 24
Record ID
BIM-650462