The role of intravenous magnesium sulphate in attenuating pressor response to laryngoscopy and intubation in patients undergoing major head and neck surgeries
Joint Authors
Sunil, Rajan
Vijay, Shankar
Jerry, Paul
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 7, Issue 3 (31 Dec. 2014), pp.451-455, 5 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2014-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background Elevation in blood pressure and heart rate (HR) following laryngoscopy and tracheal intubation, although brief, may have detrimental effects in high-risk patients.
Aim of the study To assess the role of intravenous magnesium sulphate in attenuating pressor response to laryngoscopy and intubation in patients undergoing major head and neck surgeries.
Settings and design This was a randomized, observational, pilot study.
Materials and methods One hundred patients undergoing major head and neck surgeries were divided into two groups : A and B.
Patients in group A received intravenous magnesium sulphate 50 mg/kg body weight 10 min before induction of general anaesthesia and those in group B received intravenous lignocaine 1.5 mg/kg body weight 90 s before intubation.
HR, systolic blood pressure, diastolic blood pressure and mean arterial pressures were recorded immediately after starting the intravenous line (baseline), just before induction, 1, 3, 5, 10, 15 and 30 min after intubation.
Statistical analysis Normal test for means and normal test for signifi cant difference between two proportions were used.
Results In group A, there was a statistically signifi cant decrease in HR from the preinduction values at 1, 3, 5, 10 and 15 min following intubation.
Although there was a decrease in systolic blood pressure, diastolic blood pressure and mean arterial pressures from induction values in both groups, there was no signifi cant difference between the groups.
Conclusion Intravenous magnesium sulphate effectively attenuated both HR and arterial blood pressure responses to laryngoscopy and intubation compared with intravenous lignocaine.
American Psychological Association (APA)
Sunil, Rajan& Vijay, Shankar& Jerry, Paul. 2014. The role of intravenous magnesium sulphate in attenuating pressor response to laryngoscopy and intubation in patients undergoing major head and neck surgeries. Ain Shams Journal of Anesthesiology،Vol. 7, no. 3, pp.451-455.
https://search.emarefa.net/detail/BIM-651807
Modern Language Association (MLA)
Sunil, Rajan…[et al.]. The role of intravenous magnesium sulphate in attenuating pressor response to laryngoscopy and intubation in patients undergoing major head and neck surgeries. Ain Shams Journal of Anesthesiology Vol. 7, no. 3 (Sep. / Dec. 2014), pp.451-455.
https://search.emarefa.net/detail/BIM-651807
American Medical Association (AMA)
Sunil, Rajan& Vijay, Shankar& Jerry, Paul. The role of intravenous magnesium sulphate in attenuating pressor response to laryngoscopy and intubation in patients undergoing major head and neck surgeries. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 3, pp.451-455.
https://search.emarefa.net/detail/BIM-651807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 454-455
Record ID
BIM-651807