Miltefosine efficacy on leishmania donovani promastigote
Other Title(s)
فاعلية الملتيفوسين على الطور أمامي السوط للشمانيا الأحشائية
Joint Authors
Source
Issue
Vol. 56, Issue 4A (31 Dec. 2015), pp.2811-2821, 11 p.
Publisher
University of Baghdad College of Science
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Topics
Abstract EN
In the current study, different concentrations of miltefosine drug, which is the first effective and safe oral treatment for visceral leishmaniasis, was evaluated against L.
donovani promastigotes in comparison with pentosam drug.
Direct counting microscopic assay was used to find 50% inhibitory concentration (IC50) of miltefosine and pentostam against L.
donovani promastigotes.
The IC50 of miltefosine drug was 45.42μg / ml, 46.76μg/ml and 36.68μg/ml after 24 hr, 48hr and 72hr respectively, In comparison with IC 50 of pentostam drug was 75.39 μg/ml after 72hr.
There were significant differences (P˂0.05) between IC50 values of miltefosine and pentostam drugs from first day to third day.
American Psychological Association (APA)
al-Shakir, Bara Ahmad& al-Rawi, Khawlah Hawari Zughayr. 2015. Miltefosine efficacy on leishmania donovani promastigote. Iraqi Journal of Science،Vol. 56, no. 4A, pp.2811-2821.
https://search.emarefa.net/detail/BIM-651867
Modern Language Association (MLA)
al-Shakir, Bara Ahmad& al-Rawi, Khawlah Hawari Zughayr. Miltefosine efficacy on leishmania donovani promastigote. Iraqi Journal of Science Vol. 56, no. 4A (2015), pp.2811-2821.
https://search.emarefa.net/detail/BIM-651867
American Medical Association (AMA)
al-Shakir, Bara Ahmad& al-Rawi, Khawlah Hawari Zughayr. Miltefosine efficacy on leishmania donovani promastigote. Iraqi Journal of Science. 2015. Vol. 56, no. 4A, pp.2811-2821.
https://search.emarefa.net/detail/BIM-651867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 2819-2821
Record ID
BIM-651867
