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Arterial versus venous blood samples for monitoring of activated clotting time during open heart surgery and its correlation with postoperative bleeding and reopening
Joint Authors
Afifi, Ihab E.
al-Din, Sana S.
Amir, Khalid A.
Abd al-Hamid, Ahmad M.
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 7, Issue 3 (31 Dec. 2014), pp.304-308, 5 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2014-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Objective The aim of this study was to compare between arterial and venous sampling for activated clotting time (ACT) monitoring during cardiac surgery, and to record incidence of postoperative bleeding and reopening in both the situations.
Patients and methods This prospective, comparative, double-blind study was conducted on 100 patients with heart disease undergoing open heart surgery, using systemic heparinization, cardiopulmonary bypass, and protamine reversal.
Patients were randomly allocated into two equal groups.
In group I, arterial ACT was used as a guide for heparinization and heparin reversal.
In group II, venous ACT was used as a guide for heparinization and heparin reversal.
Each patient in both groups had simultaneous arterial and venous ACT carried out at the following time points: baseline, after heparinization, 10 min after heparinization, and after protamine administration.
All patients were monitored for the amount of bleeding from the chest tube during the fi rst 3 h postoperatively and the incidence of reopening after surgery for the fi rst 24 h postoperatively.
Results Baseline venous ACT was signifi cantly higher than arterial ACT, whereas after heparinization and after blood collection, venous ACT became signifi cantly lower.
After administration of protamine, venous ACT was nonsignifi cantly lower than arterial ACT.
Blood loss was signifi cantly increased in the venous group than in the arterial group.
With regard to the incidence of reopening, there was an increase in the rate of reopening in the venous group than in the arterial group.
Conclusion There is great individual variability between the venous and arterial ACT measures.
The use of arterial samples for ACT measurement had lesser rates of postoperative bleeding and reopening.
American Psychological Association (APA)
al-Din, Sana S.& Afifi, Ihab E.& Abd al-Hamid, Ahmad M.& Amir, Khalid A.. 2014. Arterial versus venous blood samples for monitoring of activated clotting time during open heart surgery and its correlation with postoperative bleeding and reopening. Ain Shams Journal of Anesthesiology،Vol. 7, no. 3, pp.304-308.
https://search.emarefa.net/detail/BIM-652111
Modern Language Association (MLA)
al-Din, Sana S.…[et al.]. Arterial versus venous blood samples for monitoring of activated clotting time during open heart surgery and its correlation with postoperative bleeding and reopening. Ain Shams Journal of Anesthesiology Vol. 7, no. 3 (Sep. / Dec. 2014), pp.304-308.
https://search.emarefa.net/detail/BIM-652111
American Medical Association (AMA)
al-Din, Sana S.& Afifi, Ihab E.& Abd al-Hamid, Ahmad M.& Amir, Khalid A.. Arterial versus venous blood samples for monitoring of activated clotting time during open heart surgery and its correlation with postoperative bleeding and reopening. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 3, pp.304-308.
https://search.emarefa.net/detail/BIM-652111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 307-308
Record ID
BIM-652111