New imidazo [2, 1-b]naphtha [2, 1-d][1, 3] thiazole derivatives : synthesis, antimicrobial and antifungal activity
Other Title(s)
تحضير مشتقات جديدة من [2،1-b] نفثا [1,3] [2،1-d] ثايزول : اختبار الفعالية الميكروبية و المضادات الفطرية
Author
al-Lami, Nuaymah Jabbar Uwayyid
Source
Issue
Vol. 56, Issue 4C (31 Dec. 2015), pp.3274-3284, 11 p.
Publisher
University of Baghdad College of Science
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract EN
A series of new derivatives of imidazo[2,1-b]naphtha[2,1-d][1,3]thiazole were synthesised, which they are substituted at position 2.
Then, the new prepared imidazo thiazole derivatives were reacted with N,N-dimethyl formamide (DMF) and POCl3 to obtain new aldehyde derivatives at position 3.
The new aldehyde derivatives underwent condensation reaction with the hydrazine afforded new hydrazone derivatives.
The new compounds were characterized by spectra [IR, 1HNMR, 13CNMR, 2D NMR ( hsqc spectra)].
The synthesised compounds were examined the antimicrobial and antifungal activities, their antimicrobial activities against Escherichia coli, Streptococcus faecalis, Aeromonas hydrophila and Staphylococcus aureus were examined.
Most of these compounds demonstrated antimicrobial activity.
Interestingly, most of hydrazone derivatives showed antifungal activity towards spore germe and hyphae growth.
American Psychological Association (APA)
al-Lami, Nuaymah Jabbar Uwayyid. 2015. New imidazo [2, 1-b]naphtha [2, 1-d][1, 3] thiazole derivatives : synthesis, antimicrobial and antifungal activity. Iraqi Journal of Science،Vol. 56, no. 4C, pp.3274-3284.
https://search.emarefa.net/detail/BIM-652887
Modern Language Association (MLA)
al-Lami, Nuaymah Jabbar Uwayyid. New imidazo [2, 1-b]naphtha [2, 1-d][1, 3] thiazole derivatives : synthesis, antimicrobial and antifungal activity. Iraqi Journal of Science Vol. 56, no. 4C (2015), pp.3274-3284.
https://search.emarefa.net/detail/BIM-652887
American Medical Association (AMA)
al-Lami, Nuaymah Jabbar Uwayyid. New imidazo [2, 1-b]naphtha [2, 1-d][1, 3] thiazole derivatives : synthesis, antimicrobial and antifungal activity. Iraqi Journal of Science. 2015. Vol. 56, no. 4C, pp.3274-3284.
https://search.emarefa.net/detail/BIM-652887
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 3284
Record ID
BIM-652887