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Dexmedet omidine versus clonidine as an adjunct to intrathecal small dose ropivacaine in patients undergoing transurethral resection of prostate
Joint Authors
Dhasmana, Satish
Singh, Vinita
Pal, Mahendra
Raman, Rajesh
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 7, Issue 4 (31 Dec. 2014), pp.534-538, 5 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2014-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
It is important to limit the cephalad spread of local anesthetic above T10 dermatome during spinal anesthesia in patients undergoing transurethral resection of prostate (TURP).
This can be achieved by using small dose of local anesthetics in combination with intrathecal additives such as α2-agonists, which improve the quality of block without altering the height of block.
Aims The aim of the study was to compare dexmedetomidine and clonidine when added to intrathecal ropivacaine in patients undergoing TURP.
Settings and design The study was designed as a prospective, randomized, and double-blind study.
Materials and methods Fifty patients of ASA grade I –III, scheduled for elective TURP, were allocated into two groups.
Group I received 7.5 mg ropivacaine+15 μg clonidine and group II received 7.5 mg ropivacaine+5 μg dexmedetomidine.
Spinal anesthesia was administered in the sitting position after preloading the patients with 10 ml/kg Ringer’s lactate.
Onset, duration, and peak sensory level, intensity of motor block, and analgesic requirements were recorded.
Results Patients in both groups had comparable baseline and demographic characteristics.
Peak sensory block was similar in both groups.
Patients in group II had faster onset and longer duration of sensory block.
Intensity and duration of motor block were also greater in group II.
The quality of intraoperative and postoperative analgesia was better in group II.
Conclusion Intrathecal dexmedetomidine with ropivacaine provides faster onset, better operating conditions, and patient comfort in patients undergoing TURP.
However, it is associated with delayed motor recovery.
American Psychological Association (APA)
Dhasmana, Satish& Singh, Vinita& Raman, Rajesh& Pal, Mahendra. 2014. Dexmedet omidine versus clonidine as an adjunct to intrathecal small dose ropivacaine in patients undergoing transurethral resection of prostate. Ain Shams Journal of Anesthesiology،Vol. 7, no. 4, pp.534-538.
https://search.emarefa.net/detail/BIM-653669
Modern Language Association (MLA)
Dhasmana, Satish…[et al.]. Dexmedet omidine versus clonidine as an adjunct to intrathecal small dose ropivacaine in patients undergoing transurethral resection of prostate. Ain Shams Journal of Anesthesiology Vol. 7, no. 4 (Oct. / Dec. 2014), pp.534-538.
https://search.emarefa.net/detail/BIM-653669
American Medical Association (AMA)
Dhasmana, Satish& Singh, Vinita& Raman, Rajesh& Pal, Mahendra. Dexmedet omidine versus clonidine as an adjunct to intrathecal small dose ropivacaine in patients undergoing transurethral resection of prostate. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 4, pp.534-538.
https://search.emarefa.net/detail/BIM-653669
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 538
Record ID
BIM-653669