Chlamydial antibodies : pro-inflammatory cytokines and bacterial significance among infertile women

Abstract EN

The current study was done to investigate the relation between the bacteria different kindsandinfertility in women, the study include 108 specimen from infertile and fertilewomen with ages range (20-40years) these specimens collected from infertility and gynecology center of Maternity and Pediatrics Teaching Hospital in Babylon province.

Urine, vaginal swabs and blood samples were used in this study.

Bacteriological diagnosis for urine and vaginal swabs accomplished and showed variation in types and number of isolates.The isolates can be distributed as follows:Gram positive bacterial isolates include Staphylococcus aureus 48 (30%) 18 isolates urine and 30vaginal swabs, Escherichia coli24urine and 19 vaginal swabs43(26.8%).

Female infertility divided according to their causesinto different types and the detection by anti-Chlamydia trachomatis antibodies reveals high concentration of IgG (46 %) in the women with Polycystic ovary syndrome group,while the second high concentration (36 %) in women with primary infertility .

Immunological test of Cytokine IL-10 in patient show decreased in their concentration 11.5pg / ml compared with healthy at P < 0.05 especially at polycystic ovary syndrome group.