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Association of the T45G polymorphism of adiponectin gene with polycystic ovary syndrome in women of Babylon Province-Iraq
Author
Source
Issue
Vol. 12, Issue 4 (31 Dec. 2015), pp.1020-1026, 7 p.
Publisher
University of Babylon College of Medicine
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
Polycystic Ovarian syndrome (PCOS) is being the most frequent cause of anovulatory infertility, Adiponectin is the most abundantadipocytokine and may play a role in the regulation of insulin sensitivity and IR in PCOS and count for 0.01% or 3–30 μg/ml of total plasma proteinthe adiponectin gene contains 3 exons spans 16 kb on chromosome3q27.The aim of the present study was to evaluate the genetic influence of the adiponectin gene polymorphisms in the development of PCOS among women of Babylon Province/ Iraq.
sixty three women were studied ,and were classified into two groups of : first group consists of 32 women infected with polycystic ovaries syndrome, the second consists of 31 healthy women to detect the presence of T45G polymorphism within the gene.
From all subjects a whole-blood sample was taken and was used for isolation of peripheral blood leukocytes.
The adiponectin T45G polymorphism, located in exon 2, was genotyped by amplification of genomic DNA.The present study included study of the relationship of this gene with PCOS women in reproductive age, A statistically significant difference was observed in the frequency of TT,TG and GG genotypes between women with PCOS and controls
American Psychological Association (APA)
al-Musawi, Hawra Sabah. 2015. Association of the T45G polymorphism of adiponectin gene with polycystic ovary syndrome in women of Babylon Province-Iraq. Medical Journal of Babylon،Vol. 12, no. 4, pp.1020-1026.
https://search.emarefa.net/detail/BIM-656427
Modern Language Association (MLA)
al-Musawi, Hawra Sabah. Association of the T45G polymorphism of adiponectin gene with polycystic ovary syndrome in women of Babylon Province-Iraq. Medical Journal of Babylon Vol. 12, no. 4 (2015), pp.1020-1026.
https://search.emarefa.net/detail/BIM-656427
American Medical Association (AMA)
al-Musawi, Hawra Sabah. Association of the T45G polymorphism of adiponectin gene with polycystic ovary syndrome in women of Babylon Province-Iraq. Medical Journal of Babylon. 2015. Vol. 12, no. 4, pp.1020-1026.
https://search.emarefa.net/detail/BIM-656427
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1024-1026
Record ID
BIM-656427