Detection of rheumatoid factor (RF)‎-Iso types and some immunological interactions in patients with (rheumatoid arthritis-RA)‎ in Thi-Qar Provence-Iraq

Abstract EN

Rheumatoid factor (RF) produce in rheumatoid arthritis (RA)disease associated with effect of some environment factors and smoking .

In this study, we investigated whether the association between RF production and smoking was influenced by duration of disease.

the samples were taken from fifty patients with RA ,that achieved four or more criteria of the 2010 American college of Rheumatology , the sample of control 20 healthy person were used the level of RF –iso type concentration was detect in serum of patients of control group .

the samples of the present study were taken from the rheumatology department of AL-Hussein General Teaching Hospital in Thi-Qar province from beginning of September 2012 into end of march 2013.

The result shown high concentration of IgG -RF ,IgM-RF and IgA-RF (0.227,0.092and 0.245) respectively compare with control( 0.102,0.095 and 0.092).

with high statistically significant (P<0.001).Between studied group and control with IgM-RF,IgG-RF, and slightly statistically significant between studied groups(P<0.05).

,in IgA.