Platelet count to spleen diameter ratio and to spleen area ratio as predictors for esopha-geal varices in chronic hepatitis C patients with liver cirrhosis
Author
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 45, Issue 3 (31 Dec. 2015), pp.485-492, 8 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2015-12-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Endoscopic detection of esophageal varices (EV) especially the high risk esophageal varices (HREV) is recommended in cirrhotic patients.
There are several studies about non-invasive markers to predict the presence of EV.
The aim of this study was to evaluate platelet count to spleen diameter (P / D) ratio and platelet count to spleen area (P / A) ratio as predictors for EV and HREV in patients with liver cirrhosis.
This prospective study included 100 cirrhotic patients without previous variceal hemorrhage or endoscopic intervesion.
Biochemical, imaging and endoscopic findings were collected in all patients.
Several parameters including P / D and P/A ratio were measured and their association with the presence of EV and HREV was tested.
The results showed that only P/D and P / A ratios were found to be independent predictors for the presence of EV and HREV in multivariant analysis.
For prediction of the EV formation in cirrhotic patients, P/D ratio at value ≤979.9 and P / A ratio of ≤20.6 had area under the curve (AUC) 0.922 and 0.975 respectively with sensitivity 100 %, specificity 30 % for P/D ratio and sensitivity 100 %, specificity 75 % for P/A ratio.
For prediction of the HREV formation, P/D ratio at value ≤≤587.9 and P/A ratio of ≤13.7 had AUC 0.867 and 0.991 respectively with sensitivity 100 %, specificity 50 % for P / D ratio and sensitivity 100 %, specificity 88 % for P / A ratio
American Psychological Association (APA)
al-Baridi, Ashraf M.. 2015. Platelet count to spleen diameter ratio and to spleen area ratio as predictors for esopha-geal varices in chronic hepatitis C patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology،Vol. 45, no. 3, pp.485-492.
https://search.emarefa.net/detail/BIM-668454
Modern Language Association (MLA)
al-Baridi, Ashraf M.. Platelet count to spleen diameter ratio and to spleen area ratio as predictors for esopha-geal varices in chronic hepatitis C patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology Vol. 45, no. 3 (Dec. 2015), pp.485-492.
https://search.emarefa.net/detail/BIM-668454
American Medical Association (AMA)
al-Baridi, Ashraf M.. Platelet count to spleen diameter ratio and to spleen area ratio as predictors for esopha-geal varices in chronic hepatitis C patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology. 2015. Vol. 45, no. 3, pp.485-492.
https://search.emarefa.net/detail/BIM-668454
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 492
Record ID
BIM-668454