Antiparasitic activity of silver and copper oxide nanoparticles against entamoeba histolytica and cryptosporidium parvum cysts

Joint Authors

Sad, Abd al-Halim A.
Azzam, Ahmad M.
Mustafa, Amr B.
Sulayman, Muhammad

Source

Journal of the Egyptian Society of Parasitology

Issue

Vol. 45, Issue 3 (31 Dec. 2015), pp.593-602, 10 p.

Publisher

The Egyptian Society of Parasitology

Publication Date

2015-12-31

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Biology

Abstract EN

Nanoparticles (NPs) have received more attention as antiparasitic agents.

In the present study, silver and copper nanoparticles were synthesized and characterized using scanning electron microscopy (SEM), transmission electron microscope (TEM) and X-ray fluorescence (XRF).

The antiparasitic activity of Ag and CuO nanoparticles were tested against two of the most environmentally spread parasites in Egypt (Entamoeba histolytica and Cryptosporidium parvum).

The average sizes of synthesized Ag NPs and CuO NPs were 9 & 29 nm respectively and a significant reduction for cysts viability (p > 0.05) was observed for CuO NPs against E.

histolytica cysts and Ag NPs against C.

parvum oocysts.

Moreover, LC50-3h of CuO NPs for E.

histolytica and C.

parvum were 0.13 and 0.72 mg/l, while Ag NPs recorded 0.34 and 0.54 mg/l respectively.

Accordingly, these NPs could be suggested as a new nanoform agent for safe and effective treatment of E.

histolytica and C.

parvum parasites.

American Psychological Association (APA)

Sad, Abd al-Halim A.& Sulayman, Muhammad& Azzam, Ahmad M.& Mustafa, Amr B.. 2015. Antiparasitic activity of silver and copper oxide nanoparticles against entamoeba histolytica and cryptosporidium parvum cysts. Journal of the Egyptian Society of Parasitology،Vol. 45, no. 3, pp.593-602.
https://search.emarefa.net/detail/BIM-668975

Modern Language Association (MLA)

Sad, Abd al-Halim A.…[et al.]. Antiparasitic activity of silver and copper oxide nanoparticles against entamoeba histolytica and cryptosporidium parvum cysts. Journal of the Egyptian Society of Parasitology Vol. 45, no. 3 (Dec. 2015), pp.593-602.
https://search.emarefa.net/detail/BIM-668975

American Medical Association (AMA)

Sad, Abd al-Halim A.& Sulayman, Muhammad& Azzam, Ahmad M.& Mustafa, Amr B.. Antiparasitic activity of silver and copper oxide nanoparticles against entamoeba histolytica and cryptosporidium parvum cysts. Journal of the Egyptian Society of Parasitology. 2015. Vol. 45, no. 3, pp.593-602.
https://search.emarefa.net/detail/BIM-668975

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 600-602

Record ID

BIM-668975