Prevalence of secondary hyperparathyroidism among hemodialysis patients in three Royal Medical Services Centers
Joint Authors
Shibli, Husayn
Shiab, Samir
Bdirat, Amir
Qdah, Amin
Haddad, Ayham
Hijazat, Mundhir
Source
Journal of the Royal Medical Services
Issue
Vol. 22, Issue 4 (31 Dec. 2015), pp.12-17, 6 p.
Publisher
The Royal Medical Services Jordan Armed Forces
Publication Date
2015-12-31
Country of Publication
Jordan
No. of Pages
6
Main Subjects
Topics
Abstract EN
Objective: To determine the prevalence of secondary hyperparathyroidism among hemodialysis patients treated in three different centers.
Methods: This is a descriptive study conducted by reviewing patient's medical records, Patients receiving hemodialysis therapy in three different centers: King Hussein Medical Center in Amman, Prince Hashem Hospital in Zarka, and Prince Ali Hospital in Karak, representing various governorate of Jordan.
Patients included in the study were treated by hemodialysis for more than 6 months and have not had parathyroidectomy.
We screened our patients for the purpose of the study during January 2014.
Their laboratory values including serum creatinine, BUN, calcium, phosphorous, alkaline phosphatase and intact parathyroid hormone were recorded.
Depending on the iPTH level, patients were divivded into three groups, adynamic bone disease group with iPTH levels less than 130pg/ml, euparathyroid group with iPTH within the target range for hemodialysis patients (130-210pg/ml), and secondary hyperparathyroidism group with iPTH more than 210pg/ml.
Results: A total of 276 patients were included in this study.
Males were 56.5% and females 43.5%, their age ranged from 23 to 87 years with duration of hemodialysis ranged from 6 to 300 months.
Majority of patients (77.5%) found to have secondary hyperparathyroidism with an average intact parathyroid hormone level of 887.1pg/ml.
The remaining patients showed either acceptable average intact parathyroid hormone level for the hemodialysis patients 127.7pg/ml (13.4%) or showed low average intact parathyroid level of 32.9pg/ml indicating the presence of the more serious adynamic bone disease (9.1%).
Conclusion: Despite advancing hemodialysis treatment facilities and the use of calcium containing phosphorous binders and vitamin D analogue the incidence of secondary hyperparathyroidism remains high.
This may represent late referral to nephrology care or may indicate poor patient compliance to the prescribed medications.
Additional efforts should be implemented to enhance early referral of patients with chronic kidney disease to nephrology care.
American Psychological Association (APA)
Haddad, Ayham& Shibli, Husayn& Hijazat, Mundhir& Shiab, Samir& Bdirat, Amir& Qdah, Amin. 2015. Prevalence of secondary hyperparathyroidism among hemodialysis patients in three Royal Medical Services Centers. Journal of the Royal Medical Services،Vol. 22, no. 4, pp.12-17.
https://search.emarefa.net/detail/BIM-673919
Modern Language Association (MLA)
Haddad, Ayham…[et al.]. Prevalence of secondary hyperparathyroidism among hemodialysis patients in three Royal Medical Services Centers. Journal of the Royal Medical Services Vol. 22, no. 4 (Dec. 2015), pp.12-17.
https://search.emarefa.net/detail/BIM-673919
American Medical Association (AMA)
Haddad, Ayham& Shibli, Husayn& Hijazat, Mundhir& Shiab, Samir& Bdirat, Amir& Qdah, Amin. Prevalence of secondary hyperparathyroidism among hemodialysis patients in three Royal Medical Services Centers. Journal of the Royal Medical Services. 2015. Vol. 22, no. 4, pp.12-17.
https://search.emarefa.net/detail/BIM-673919
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 16-17
Record ID
BIM-673919