Pregnancy after renal transplantation : effects on mother, child, and renal graft function
Joint Authors
al-Husni, Siham
Sabri, Siham
Rhou, Hakimah
Bin Ammar, Lubna
Ouzeddoun, Nuaymah
Bayahia, Rabiah
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 2 (30 Apr. 2016), pp.227-232, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-04-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
The aim of this study was to report our experience of pregnancy in renal transplant (RT) patients and its medium and long-term effects on the renal graft as well as the maternal fetal complications.
We studied 21 pregnancies in 12 RT patients with mean age of 29.9 ± 5.3 years.
The mean duration of RT to 1st pregnancy was 42 (21–68.5) months and the median follow-up period was 112.5 (138–165) months.
The pregnancy was planned in 28.6 % of the cases.
At the time of the diagnosis of the pregnancy, all the patients were maintained on corticosteroids and cyclosporine, 14.3 % of the patients were on mycophenolate mofetil, and 71.4 % of the patients were on azathioprine.
The high blood pressure was present before the pregnancy in 33.3 % of the patients.
During pregnancy, proteinuria appeared in 20% of the cases, urinary tract infection in 33.3 %, and preeclampsia in 5 %.
Anemia was present in all the patients during pregnancy.
The doses of cyclosporine were increased during pregnancy.
The mean term of delivery was 37 ± 2 weeks.
Premature delivery was observed in 19 % of the cases, fetal death in utero in 10 %, and abortion in 15 %.
The number of living children was 16, with a mean birth weight of 3014 ± 515 g; the weight was lower than 2500 g in three (15 %) cases.
In the long-term follow-up, we noticed two cases of acute rejection related to patients’ noncompliance, and four cases of chronic allograft nephropathy, without a switch to dialysis.
We conclude that pregnancy in RT patients requires multidisciplinary care because of the increased risks of maternal and fetal complications.
Each pregnancy needs to be planned; all parameters have to be studied and evaluated in order to allow for optimization of outcome and minimization of complications.
American Psychological Association (APA)
al-Husni, Siham& Sabri, Siham& Bin Ammar, Lubna& Ouzeddoun, Nuaymah& Bayahia, Rabiah& Rhou, Hakimah. 2016. Pregnancy after renal transplantation : effects on mother, child, and renal graft function. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 2, pp.227-232.
https://search.emarefa.net/detail/BIM-677888
Modern Language Association (MLA)
al-Husni, Siham…[et al.]. Pregnancy after renal transplantation : effects on mother, child, and renal graft function. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 2 (Mar. / Apr. 2016), pp.227-232.
https://search.emarefa.net/detail/BIM-677888
American Medical Association (AMA)
al-Husni, Siham& Sabri, Siham& Bin Ammar, Lubna& Ouzeddoun, Nuaymah& Bayahia, Rabiah& Rhou, Hakimah. Pregnancy after renal transplantation : effects on mother, child, and renal graft function. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 2, pp.227-232.
https://search.emarefa.net/detail/BIM-677888
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 231-232
Record ID
BIM-677888