Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D : the OCEANOS study
Joint Authors
Kashif, Waqar Uddin
Kurpad, Ramprasad
al-Syyari, Abd Allah
Suqya, Muhammad Ziyad
al-Jabburi, Harith
Tuganbekova, Saltanat
Kabulbayev, Khairat
al-Baz, Tariq
Shahin, Faysal A. M.
Nafar, Muhsin
Jarraya, Faisal
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 27, Issue 2 (30 Apr. 2016), pp.290-304, 15 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2016-04-30
Country of Publication
Saudi Arabia
No. of Pages
15
Main Subjects
Topics
Abstract EN
Our aim is to assess the current clinical practices in monitoring and treatment patterns of chronic kidney disease (CKD)-mineral bone disorder and the degree to which these practices met the kidney disease improving global outcome (KDIGO) guidelines.
This was an international, multi-center, cross-sectional, observational study in adult patients diagnosed with CKD Stages 4, 5, and 5D.
Patients were enrolled from Middle East, South Asia, Eurasia, and Africa; patients with estimated glomerular filtration rate ≥30 mL/min/1.73 m2 or with any medical/surgical conditions precluding their participation were excluded.
Frequency of measurements, levels of serum calcium (Ca), phosphorus and parathormone (parathyroid hormone [PTH]), and presence vascular/valvular calcification were recorded.
Of the 2250 patients enrolled, data on 2247 patients were evaluated.
Overall, only a small percentage of patients met all three target KDIGO ranges of serum Ca, phosphorus, and PTH (13.7 % [95 % confidence interval : 12.0 ; 15.4]), with a higher proportion among CKD Stage 5D patients (14.8 %) than CKD Stage 4 and 5 (5.6 %) patients.
Majority (84.3 %) of the patients received treatment with phosphorous binders, of whom 85.5 % received Ca-based phosphate binders.
Overall, 57.0 % of patients received Vitamin D
American Psychological Association (APA)
Shahin, Faysal A. M.& Kurpad, Ramprasad& al-Syyari, Abd Allah& Suqya, Muhammad Ziyad& al-Jabburi, Harith& al-Baz, Tariq…[et al.]. 2016. Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D : the OCEANOS study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 2, pp.290-304.
https://search.emarefa.net/detail/BIM-677938
Modern Language Association (MLA)
Shahin, Faysal A. M.…[et al.]. Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D : the OCEANOS study. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 2 (Mar. / Apr. 2016), pp.290-304.
https://search.emarefa.net/detail/BIM-677938
American Medical Association (AMA)
Shahin, Faysal A. M.& Kurpad, Ramprasad& al-Syyari, Abd Allah& Suqya, Muhammad Ziyad& al-Jabburi, Harith& al-Baz, Tariq…[et al.]. Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D : the OCEANOS study. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 2, pp.290-304.
https://search.emarefa.net/detail/BIM-677938
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 302-304
Record ID
BIM-677938