Survey on hypothermia and hyperthermia in poisoned patients in Unique Referral Hospital, Tehran, Iran
Joint Authors
Hashimiyan, Murtada
Talaie, Haleh
Mahdavinejad, Arezou
Muzaffari, Nasir
Shoaei, Simin Dokht
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 4 (30 Apr. 2016), pp.1-8, 8 p.
Publisher
Publication Date
2016-04-30
Country of Publication
United Arab Emirates
No. of Pages
8
Main Subjects
Abstract EN
Background: Body temperature is a critical criterion of health.
Drugs and a variety of poisons can affect body temperature in poisoned patients, causing hyperthermia and hyperpyrexia.
Objectives: Our previous study’s findings in patients poisoned with organophosphate led us to the goal of this study: obtaining the initial tympanic temperature in patients poisoned by a variety of toxins.
Materials and Methods: A cross-sectional study reviewed the records of poisoned patients who were admitted to the toxicological intensive care unit (TICU) at Loghman Hakim hospital poison center (LHHPC) from February 2014 to February 2015.
The data collected included gender, age, type of poisoning, the season during which poisoning occurred, vital signs, initial tympanic temperature (first four hours), presence of seizures, white blood cell (WBC) count, creatinine phosphokinase (CPK), length of stay and patient outcome.
We determined the mean (SD) for normally distributed continuous variables, the median and interquartile range for non-normally distributed continuous variables, and the absolute and relative frequency (%) for categorical variables.
All were determined using SPSS version 16.
Results: Data were collected from 310 eligible patients.
The mean patient age was 32.65 (with a standard deviation of 14.40).
Of the patients in the study, 183 (59%) were male.
Intentional poisoning in an attempted suicide was documented in 253 (81.6%) patients.
The most prevalent poisoning agent was aluminum phosphate (18.70%), followed by methadone (10%) and opium (10%).
Seventy percent of the patients (n = 217) were diagnosed with fever or hyperthermia.
A temperature 40°C was detected in just three cases.
The highest mean temperature was found in patients poisoned with amphetamine, organophosphate or tramadol.
Patients with alcohol and phenobarbital poisoning were included in the sample, but these patients were not diagnosed with hypothermia.
WBC 10,000 cells/mL and CPK 975 IU/L were recorded in 57.7% and 13.2% of subjects, respectively.
Conclusions: Body temperature changes in human poisonings are a matter in need of special attention.
A literature review did not reveal any controversy over hypothermia, but poisoning cases exhibit a variety of patterns of fever and hyperthermia.
If there are no limits to the diagnosis of fever and hyperthermia, all cases with a poor prognosis which fail to respond to treatment could be categorized as drug-induced hyperthermia.
Therefore, a different approach is needed for poisoning cases.
American Psychological Association (APA)
Muzaffari, Nasir& Talaie, Haleh& Shoaei, Simin Dokht& Hashimiyan, Murtada& Mahdavinejad, Arezou. 2016. Survey on hypothermia and hyperthermia in poisoned patients in Unique Referral Hospital, Tehran, Iran. Iranian Red Crescent Medical Journal،Vol. 18, no. 4, pp.1-8.
https://search.emarefa.net/detail/BIM-679207
Modern Language Association (MLA)
Muzaffari, Nasir…[et al.]. Survey on hypothermia and hyperthermia in poisoned patients in Unique Referral Hospital, Tehran, Iran. Iranian Red Crescent Medical Journal Vol. 18, no. 4 (Apr. 2016), pp.1-8.
https://search.emarefa.net/detail/BIM-679207
American Medical Association (AMA)
Muzaffari, Nasir& Talaie, Haleh& Shoaei, Simin Dokht& Hashimiyan, Murtada& Mahdavinejad, Arezou. Survey on hypothermia and hyperthermia in poisoned patients in Unique Referral Hospital, Tehran, Iran. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 4, pp.1-8.
https://search.emarefa.net/detail/BIM-679207
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 7-8
Record ID
BIM-679207