The effects of proximal and distal social stimulation on ethanol intake in male and female CD-1 mice
Joint Authors
Yu, Lei
Tomie, Arthur
Samuel, Allison Gayle
Merchant, Alam
Source
Journal of Drug and Alcohol Research
Issue
Vol. 5, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Publication Date
2016-12-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Topics
Abstract EN
Background.
Proximal and distal social stimulation increase ethanol drinking in humans.
Purpose.
Our study evaluated the effects of proximal and distal social stimulation on home-cage ethanol drinking in mice.
Study design.
Proximal cagemate drinking (PCD) procedures use a clear plastic barrier to separate the drinker mouse from the proximal cagemate mouse, to evaluate home-cage drinking of 10% ethanol and water.
Eight groups of CD-1 mice were arranged in a 2×2×2 factorial design with two levels of sex of drinker (male vs.
female), two levels of sex of cagemate (male vs.
female), and two levels of distal group-housed mice in the colony room (present vs.
absent).
Results.
Distal group-housed mice, located outside of the home cage, stimulated ethanol drinking in female drinkers and did so regardless of the sex of their proximal cagemate.
This effect was observed in the male drinker but only when housed with a proximal male cagemate.
Conclusion.
This study provides the first report of distal social stimulation of ethanol drinking in mice.
The distal social stimulation effect, like the effects of proximal social stimulation, was more pronounced in female drinkers
American Psychological Association (APA)
Tomie, Arthur& Samuel, Allison Gayle& Merchant, Alam& Yu, Lei. 2016. The effects of proximal and distal social stimulation on ethanol intake in male and female CD-1 mice. Journal of Drug and Alcohol Research،Vol. 5, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-679431
Modern Language Association (MLA)
Tomie, Arthur…[et al.]. The effects of proximal and distal social stimulation on ethanol intake in male and female CD-1 mice. Journal of Drug and Alcohol Research Vol. 5 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-679431
American Medical Association (AMA)
Tomie, Arthur& Samuel, Allison Gayle& Merchant, Alam& Yu, Lei. The effects of proximal and distal social stimulation on ethanol intake in male and female CD-1 mice. Journal of Drug and Alcohol Research. 2016. Vol. 5, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-679431
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 8-9
Record ID
BIM-679431