Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR
Joint Authors
Meligy, Bassant
Sayyid, Amal
Ismail, Daliyah Qadri
Kamal, Dina
Abd al-Latif, Wala
Irfan, Dina M.
Source
Egyptian Pediatric Association Gazette
Issue
Vol. 64, Issue 1 (31 Mar. 2016), pp.13-19, 7 p.
Publisher
Egyptian Pediatric Association
Publication Date
2016-03-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Topics
- Respiratory system
- Pediatrics
- Pneumonia
- Infection
- Infants
- Polymerase chain reaction
- Diagnosis
- Acute diseases
Abstract EN
Introduction: Acute lower respiratory tract infection in children causes significant morbidity in the developing countries.
Documentation of virus infection using PCR and clinical characteristics of patients affected with viral pneumonia are reviewed in this study.
Methods: 51 children less than three years admitted to the Pediatric Hospital, Cairo University with viral pneumonia were included.
All patients had undergone nasopharyngeal aspirate for PCR viral detection.
Results: A total of 51 cases were enrolled in the study, of which 7 cases were negative while 44 children were positive for viruses.
The most common respiratory virus was Rhinovirus in 32 patients (72.2%), then parainfluenza virus (PIV) in 12 (27.3%), of which subtypes PIV1 were 2 (4.5%), PIV3 were 5 (11.4%) and PIV4 were 5 (11.4%) cases.
The third common viruses were respiratory syncytial virus (RSV) in 9 (20.5%) cases of which 3 (6.8%) were RSVA and 6 (13.6%) were RSVB and adenovirus in 9 cases (20.5%).
Boca virus was found in 8 (18.2%) patients, corona virus 2 (4.5%) patients, H1N1 2 (4.5%) patients, enterovirus 2 patients (4.5%) and human metapneumovirus in one case (2.3%).
Influenza B and PIV2 were not detected.
Coinfection was found in 28 (63.7%).
Mortality occurred in 12 (23.5%).
There was no significant relation between virus type or coinfection with disease severity.
Conclusions: RV was the most commonly detected virus in children under 3 years admitted with acute lower respiratory tract infections.
Coinfection was present in the majority of our patients; however it was not related significantly to parameters of disease severity.
American Psychological Association (APA)
Meligy, Bassant& Sayyid, Amal& Ismail, Daliyah Qadri& Kamal, Dina& Abd al-Latif, Wala& Irfan, Dina M.. 2016. Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR. Egyptian Pediatric Association Gazette،Vol. 64, no. 1, pp.13-19.
https://search.emarefa.net/detail/BIM-679639
Modern Language Association (MLA)
Meligy, Bassant…[et al.]. Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR. Egyptian Pediatric Association Gazette Vol. 64, no. 1 (Mar. 2016), pp.13-19.
https://search.emarefa.net/detail/BIM-679639
American Medical Association (AMA)
Meligy, Bassant& Sayyid, Amal& Ismail, Daliyah Qadri& Kamal, Dina& Abd al-Latif, Wala& Irfan, Dina M.. Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR. Egyptian Pediatric Association Gazette. 2016. Vol. 64, no. 1, pp.13-19.
https://search.emarefa.net/detail/BIM-679639
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 18-19
Record ID
BIM-679639