Synthesis and optimization of silver nanoparticles-antibody herceptin conjugation for surface-enhanced Raman scattering (SERS)‎

Other Title(s)

تصنيع و توليف جسميات مضادة للفضة باقتران هيرسبتين لاستطارة رامان ذو السطح المحسن

Joint Authors

Zahid, Nasir Jafar
Hashimi, Bijan
Rasib, Muhammad Jafad
Mohtfir, Afshin

Source

Engineering and Technology Journal

Issue

Vol. 33, Issue 9B (30 Sep. 2015), pp.1655-1662, 8 p.

Publisher

University of Technology

Publication Date

2015-09-30

Country of Publication

Iraq

No. of Pages

8

Main Subjects

Physics
Chemistry

Abstract AR

تصنیع و تولیف جسیمات مضادة نانویة للفضة باقتران ھیرسبتین لاستطارة رامان ذو السطح المحسن.

في ھذا البحث تم تطویر ركیزة لاستطارة رامان ذو السطح المحسن مكونة من جسیمات الفضة النانویة المضادة كمجس نانوي وظیفي، في ھذه الدراسة تم تصنیع جسیمات الفضة النانویة باستخدام (pMBA) كرابط للجسیمات المضادة و تم تحلیل الربط لجسیمات الفظة النانویة بواسطة جهاز (FTIR).

النتائج بینت بشكل واضح الجسیمات النانویة للفضة بأقطار ((50 μm علاوة على ذلك مجس سطح رامان المحسن بین بان جسیمات الفضة النانویة المضادة المقترنة قد حسنت حساسیة المجس بمقدار 105.

Abstract EN

We have developed surface-enhanced Raman spectroscopysubstrate composed of antibody-conjugated silver nanoparticles as a functional nanoprobe.

In this study, we synthesized silver nanoparticles with the pMBA linker for binding to antibody Herceptin and analyzed the binding of Herceptin to silver nanoparticles by Fourier Tranform Infrared (FT-IR).

Our results clearly showed that a spherical shape of silver nanoparticles with a diameter of 50 μm has been performed.

Furthermore, the obtained SERS probe apparently indicated that the intensity of antibody-conjugated silver nanoparticles as a SERS sensitive probe is increased by an enhancement factor of 105.

American Psychological Association (APA)

Zahid, Nasir Jafar& Hashimi, Bijan& Rasib, Muhammad Jafad& Mohtfir, Afshin. 2015. Synthesis and optimization of silver nanoparticles-antibody herceptin conjugation for surface-enhanced Raman scattering (SERS). Engineering and Technology Journal،Vol. 33, no. 9B, pp.1655-1662.
https://search.emarefa.net/detail/BIM-681215

Modern Language Association (MLA)

Zahid, Nasir Jafar…[et al.]. Synthesis and optimization of silver nanoparticles-antibody herceptin conjugation for surface-enhanced Raman scattering (SERS). Engineering and Technology Journal Vol. 33, no. 9B (2015), pp.1655-1662.
https://search.emarefa.net/detail/BIM-681215

American Medical Association (AMA)

Zahid, Nasir Jafar& Hashimi, Bijan& Rasib, Muhammad Jafad& Mohtfir, Afshin. Synthesis and optimization of silver nanoparticles-antibody herceptin conjugation for surface-enhanced Raman scattering (SERS). Engineering and Technology Journal. 2015. Vol. 33, no. 9B, pp.1655-1662.
https://search.emarefa.net/detail/BIM-681215

Data Type

Journal Articles

Language

English

Notes

Text in English ; abstracts in English and Arabic.

Record ID

BIM-681215