Enigmatic Inv (9)‎ : a case report on rare findings in hematological malignancies

Joint Authors

Vijay, Sangeetha
Narayanan, Geetha
Sarojam, Santhi
Raveendran, Suresh Kumar
Hariharan, Sreedharan

Source

Iranian Red Crescent Medical Journal

Issue

Vol. 18, Issue 4 (30 Apr. 2016), pp.1-5, 5 p.

Publisher

Iranian Hospital

Publication Date

2016-04-30

Country of Publication

United Arab Emirates

No. of Pages

5

Main Subjects

Medicine

Abstract EN

Introduction: Inversion of chromosome 9 had been widely discussed among geneticists and evolutionary biologists because of its significant impact on various hereditary disorders and in the evolution of man.

The role of such inversions in human disease evolution is an area hitherto unclear.

Case Presentation: We present the case of a chronic myeloid leukemia (CML) patient who showed intermittent relapse on treatment, with a rare appearance of clones with dual inversion (9) breakpoints [inv(9)(p22q34); inv(9)(p11q21)].

We also present the first report of inv(9)(p11,q13) as the sole abnormality in a patient with chronic myeloproliferative disorder(CMPD).

Both the patients registered in 2012 and were from Kerala, India.

Conclusions: Both the cases discussed in our study have inv(9) as the sole abnormality and are found to confer a relatively poor prognosis.

American Psychological Association (APA)

Vijay, Sangeetha& Narayanan, Geetha& Sarojam, Santhi& Raveendran, Suresh Kumar& Hariharan, Sreedharan. 2016. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal،Vol. 18, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-682391

Modern Language Association (MLA)

Vijay, Sangeetha…[et al.]. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal Vol. 18, no. 4 (Apr. 2016), pp.1-5.
https://search.emarefa.net/detail/BIM-682391

American Medical Association (AMA)

Vijay, Sangeetha& Narayanan, Geetha& Sarojam, Santhi& Raveendran, Suresh Kumar& Hariharan, Sreedharan. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-682391

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 5

Record ID

BIM-682391