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Enigmatic Inv (9) : a case report on rare findings in hematological malignancies
Joint Authors
Vijay, Sangeetha
Narayanan, Geetha
Sarojam, Santhi
Raveendran, Suresh Kumar
Hariharan, Sreedharan
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 18, Issue 4 (30 Apr. 2016), pp.1-5, 5 p.
Publisher
Publication Date
2016-04-30
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Abstract EN
Introduction: Inversion of chromosome 9 had been widely discussed among geneticists and evolutionary biologists because of its significant impact on various hereditary disorders and in the evolution of man.
The role of such inversions in human disease evolution is an area hitherto unclear.
Case Presentation: We present the case of a chronic myeloid leukemia (CML) patient who showed intermittent relapse on treatment, with a rare appearance of clones with dual inversion (9) breakpoints [inv(9)(p22q34); inv(9)(p11q21)].
We also present the first report of inv(9)(p11,q13) as the sole abnormality in a patient with chronic myeloproliferative disorder(CMPD).
Both the patients registered in 2012 and were from Kerala, India.
Conclusions: Both the cases discussed in our study have inv(9) as the sole abnormality and are found to confer a relatively poor prognosis.
American Psychological Association (APA)
Vijay, Sangeetha& Narayanan, Geetha& Sarojam, Santhi& Raveendran, Suresh Kumar& Hariharan, Sreedharan. 2016. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal،Vol. 18, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-682391
Modern Language Association (MLA)
Vijay, Sangeetha…[et al.]. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal Vol. 18, no. 4 (Apr. 2016), pp.1-5.
https://search.emarefa.net/detail/BIM-682391
American Medical Association (AMA)
Vijay, Sangeetha& Narayanan, Geetha& Sarojam, Santhi& Raveendran, Suresh Kumar& Hariharan, Sreedharan. Enigmatic Inv (9) : a case report on rare findings in hematological malignancies. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 4, pp.1-5.
https://search.emarefa.net/detail/BIM-682391
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 5
Record ID
BIM-682391