The association between glycemic control and microalbuminuria in type 2 diabetes

Abstract EN

Microalbuminuria is an independent risk factor for cardiovascular and renal outcome in a patient with Type 2 diabetes.

The evidence that intensive glycemic control reduces the microvascular complications of diabetes is based almost exclusively on prevention of microalbuminuria.

To evaluate the association between microalbuminuria and glycemic control and other factors in Type 2 diabetes, we studied retrospectively 551 patients with Type 2 diabetes.

The patients were divided into two groups: 175 patients with microalbuminuria in the case group and 376 with normal urine albumin-creatinine ratio in the control group.

Our data indicated that there was a significant association between the uncontrolled glycemia and development of microalbuminuria and that was more obvious if HbA1c level was >11%.

Our data also indicate that there was a statistical significant association between male gender, age, the systolic and diastolic blood pressure (DBP) levels, and the microalbuminuria in crude odds ratios (ORs).

We conclude that there was a clear association between the glycemic control and microalbuminuria, and microalbuminuria was associated with older age, male gender, and systolic and DBP in crude ORs.