Unusual indolent course of a chronic active Epstein-Barr virus-associated natural killer cell lymphoproliferative disorder
Other Title(s)
مسار بطيء التنامي غير معتاد للاضطراب التكاثري اللمفي المزمن للخلايا الفاتكة الطبيعية المرتبطة بفيروس إبيشتاين-بار
Joint Authors
al-Riyami, Arwa Z.
al-Hunini, Muhammad
al-Hadabi, Ibrahim
al-Farsi, Khalil
al-Khaburi, Murtada
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 16, Issue 2 (31 May. 2016), pp.230-233, 4 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2016-05-31
Country of Publication
Oman
No. of Pages
4
Main Subjects
Abstract EN
Natural killer (NK) cell lymphoproliferative disorders are uncommon and the Epstein-Barr virus (EBV) plays an important aetiological role in their pathogenesis.
We report a 20-year-old male with a chronic active EBV infection associated with a NK cell lymphoproliferative disorder which had an unusual indolent course.
He presented to the Sultan Qaboos University Hospital in Muscat, Oman, in December 2011 with a history of intermittent fever and coughing.
Examinations revealed generalised lymphadenopathy, hepatosplenomegaly, leukocytosis, transaminitis, diffuse bilateral lung infiltrates and bone marrow lymphocyte involvement.
A polymerase chain reaction (PCR) test revealed a high EBV viral load in the peripheral blood cells.
The patient received a course of piperacillin-tazobactam for Klebsiella pneumoniae, but no active treatment for the lymphoproliferative disorder.
However, his lymphocyte count, serum lactate dehydrogenase and liver enzymes dropped spontaneously.
In addition, EBV PCR copies fluctuated and then decreased significantly.
He remained clinically asymptomatic over the following four years
American Psychological Association (APA)
al-Riyami, Arwa Z.& al-Farsi, Khalil& al-Khaburi, Murtada& al-Hunini, Muhammad& al-Hadabi, Ibrahim. 2016. Unusual indolent course of a chronic active Epstein-Barr virus-associated natural killer cell lymphoproliferative disorder. Sultan Qaboos University Medical Journal،Vol. 16, no. 2, pp.230-233.
https://search.emarefa.net/detail/BIM-683867
Modern Language Association (MLA)
al-Riyami, Arwa Z.…[et al.]. Unusual indolent course of a chronic active Epstein-Barr virus-associated natural killer cell lymphoproliferative disorder. Sultan Qaboos University Medical Journal Vol. 16, no. 2 (May. 2016), pp.230-233.
https://search.emarefa.net/detail/BIM-683867
American Medical Association (AMA)
al-Riyami, Arwa Z.& al-Farsi, Khalil& al-Khaburi, Murtada& al-Hunini, Muhammad& al-Hadabi, Ibrahim. Unusual indolent course of a chronic active Epstein-Barr virus-associated natural killer cell lymphoproliferative disorder. Sultan Qaboos University Medical Journal. 2016. Vol. 16, no. 2, pp.230-233.
https://search.emarefa.net/detail/BIM-683867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 233
Record ID
BIM-683867