Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide : report of a case and review of all published cases
Joint Authors
Julka, P. K.
Mallick, Supriya
Haresh, K. P.
Gupta, Subhash
Giridhar, Prashanth
Rath, G. K.
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 28, Issue 2 (30 Jun. 2016), pp.111-116, 6 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2016-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction : Fibrosarcoma is a rare brain tumour with 33 cases reported so far.
However, there is no clear consensus about the nature of the disease and treatment as well as outcome.
Methods : A MEDLINE search was carried out using MESH terms like intracranial fibrosarcoma, intraspinal fibrosarcoma, fibrosarcoma meninges and fibrosarcoma brain.
A total of 22 case reports and series reporting a total of 33 cases were identified.
We here also report a case treated in our institute with adjuvant radiation and concurrent and maintenance temozolomide.
Results : The age of presentation ranged from 2 months to 75 years (Median= 17 years).
The gender ratio was found to be M : F of 1.75–1.
Treatment modalities were described for 17 cases.
Surgery was part of treatment in all cases while radiation was a part of treatment in 59% of cases (n = 10) and chemotherapy in 29 % cases (n = 5).
Survival data were available only for 8 cases and ranged from 1 day to 8 years (Median = 15.5 months).
Conclusion : Fibrosarcoma is a rare disease with dismal prognosis.
Surgery remains the cornerstone of therapy.
Radiation confers long term disease control and survival.
Chemotherapy needs to be evaluated for these tumours to improve survival.
American Psychological Association (APA)
Giridhar, Prashanth& Mallick, Supriya& Haresh, K. P.& Gupta, Subhash& Julka, P. K.& Rath, G. K.. 2016. Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide : report of a case and review of all published cases. Journal of the Egyptian National Cancer Institute،Vol. 28, no. 2, pp.111-116.
https://search.emarefa.net/detail/BIM-684381
Modern Language Association (MLA)
Giridhar, Prashanth…[et al.]. Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide : report of a case and review of all published cases. Journal of the Egyptian National Cancer Institute Vol. 28, no. 2 (Jun. 2016), pp.111-116.
https://search.emarefa.net/detail/BIM-684381
American Medical Association (AMA)
Giridhar, Prashanth& Mallick, Supriya& Haresh, K. P.& Gupta, Subhash& Julka, P. K.& Rath, G. K.. Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide : report of a case and review of all published cases. Journal of the Egyptian National Cancer Institute. 2016. Vol. 28, no. 2, pp.111-116.
https://search.emarefa.net/detail/BIM-684381
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 116
Record ID
BIM-684381