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Relations of high sensitive C-reactive protein (hs-CRP) with microalbuminuria as a useful predictor of cardiovascular risk among type 1 diabetes mellitus patients
Author
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 58, Issue 1 (31 Mar. 2016), pp.90-93, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2016-03-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Background : Inflammation and more specifically inflammatory cytokines are determinant in the development of microvascular diabetic complications, including neuropathy, retinopathy and nephropathy.
Objective : The aim of present study is to evaluate the relationships between high sensitive C-reactive protein, microalbuminuria and risk factors for cardiovascular disease.
Subjects and methods: the study involved (30) patients with type 1 diabetic mellitus compared to (30) healthy control.
A fasting blood sample was drawn from all subjects after an overnight fasting to measure the biochemical parameters which including glycated hemoglobin, lipid profile, atherogenic index of plasma and high sensitive C-reactive protein concentration in blood of all subjects, also evaluating microalbuminuria, creatinine, urea level in urine of type 1 diabetic mellitus patients and healthy control.
Results : results revealed a significant increase in the level of glycated hemoglobin, total cholesterol, triglyceride, low density lipoprotein, high sensitive C-reactive protein, microalbuminuria, urea and atherogenic index of plasma.
While a significant decrease in high density lipoprotein level in patients group compared with control group.
Also, there were a highly significant positive correlation between high sensitive C-reactive protein and glycated hemoglobin, atherogenic index of plasma and microalbuminuria.
Conclusions : the results of this study suggests that high sensitive C-reactive protein can be use with microalbuminuria as a biochemical marker to predict the early stage of cardiovascular disease in children and adolescents with type 1 diabetic mellitus.
American Psychological Association (APA)
Hasan, Abir J.. 2016. Relations of high sensitive C-reactive protein (hs-CRP) with microalbuminuria as a useful predictor of cardiovascular risk among type 1 diabetes mellitus patients. Journal of the Faculty of Medicine Baghdad،Vol. 58, no. 1, pp.90-93.
https://search.emarefa.net/detail/BIM-685284
Modern Language Association (MLA)
Hasan, Abir J.. Relations of high sensitive C-reactive protein (hs-CRP) with microalbuminuria as a useful predictor of cardiovascular risk among type 1 diabetes mellitus patients. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 1 (2016), pp.90-93.
https://search.emarefa.net/detail/BIM-685284
American Medical Association (AMA)
Hasan, Abir J.. Relations of high sensitive C-reactive protein (hs-CRP) with microalbuminuria as a useful predictor of cardiovascular risk among type 1 diabetes mellitus patients. Journal of the Faculty of Medicine Baghdad. 2016. Vol. 58, no. 1, pp.90-93.
https://search.emarefa.net/detail/BIM-685284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 92-93
Record ID
BIM-685284