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Effect of cholestyramine on gastrointestinal transit in patients with idiopathic bile acid diarrhea : a prospective, open-label study
Joint Authors
Stotzer, P. O.
Abrahamsson, H.
Bajor, A.
Sadiq, R.
Source
Neuroenterology : Journal of Neurology and Gut
Issue
Vol. 2, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Publication Date
2013-12-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Patients with idiopathic bile acid diarrhea (IBAD) have accelerated transit in the small bowel and in the colon.
This study evaluated the effect of cholestyramine, a bile acid binder, on transit in the small bowel and in the colon.
Methods.
Thirteen subjects with IBAD (4 male, 9 female; aged 23-67 years) were included.
Gastrointestinal transit was investigated in all subjects before and during treatment with cholestyramine.
Results.
Stool frequency was reduced (P <.05), and stool consistency was harder (P <.01) during treatment.
A tendency to prolonged small bowel transit time was shown (P = .05).
Transit in the transverse colon was prolonged by treatment (P < .02).
Conclusions.
A bile acid binder is an effective treatment in IBAD, probably by reducing transit in both the small bowel and in the colon.
The results also indicate that the small bowel as well as the colon has a pathophysiological role in IBAD.
American Psychological Association (APA)
Stotzer, P. O.& Abrahamsson, H.& Bajor, A.& Sadiq, R.. 2013. Effect of cholestyramine on gastrointestinal transit in patients with idiopathic bile acid diarrhea : a prospective, open-label study. Neuroenterology : Journal of Neurology and Gut،Vol. 2, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-685981
Modern Language Association (MLA)
Stotzer, P. O.…[et al.]. Effect of cholestyramine on gastrointestinal transit in patients with idiopathic bile acid diarrhea : a prospective, open-label study. Neuroenterology : Journal of Neurology and Gut Vol. 2 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-685981
American Medical Association (AMA)
Stotzer, P. O.& Abrahamsson, H.& Bajor, A.& Sadiq, R.. Effect of cholestyramine on gastrointestinal transit in patients with idiopathic bile acid diarrhea : a prospective, open-label study. Neuroenterology : Journal of Neurology and Gut. 2013. Vol. 2, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-685981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-685981