Evaluation of insulin, insulin resistance LH, and FSHin women with polycystic ovary syndrome and diabetic mellitus type 2

Abstract EN

The polycystic ovary syndrome is one of the most common causes of infertility duo to anovulation in women.In this study there was 105 women, 75 patients of them divided in to three groups, (A) 30 women with diabetic mellitus type 2, (B) 30 women with polycystic ovary syndrome, (C) 15 women with diabetic mellitus type 2 and poly cystic ovary syndrome and 30 women asa control group.In this entire group were analyzed serum fasting glucose, HbA1c, fastinginsulin,IR,LH, FSH, lipid profile, and total anti-oxidant.

The result show significant increase in fasting insulin level, and insulin resistance in type 2 diabetic patient group and DMT2 + PCOS group compared to those of control also there was a significant increase in level of LH compared to those of control(p < 0.05).

Woman with diabetic mellitus type2 and polycystic ovary syndrome have high serum insulin levels and Luteinizing hormone Insulin resistance and compensatoryhyperinsulinemia can inhibit follicular development and ovulation.