Synthesis and characterization of several new succinimides linked to phenyl azo benzothiazole or thiazole moieties with expected biological activity
Other Title(s)
تحضير و تشخيص عدد من السكسن إيمايدات الجديدة المرتبطة بمكونة فنيل أزوبنزوثايازول أو ثايازول ذات فعالية بأيولوجية متوقعة
Joint Authors
Jasim, Iman Khalil
al-Azzawi, Ahlam Maruf
Source
Issue
Vol. 57, Issue 1C (31 Mar. 2016), pp.534-544, 11 p.
Publisher
University of Baghdad College of Science
Publication Date
2016-03-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Topics
Abstract EN
In the present work, several new cyclic imides (succinimides) linked to benzothiazole or thiazole moieties through phenyl azo group were synthesized.
Synthesis of the new imides was performed via multistep synthesis.
The first step involved reaction of equimolar amounts of succinic anhydride and p-toluidine producing N-(4-tolyl) succinamic acid (1) which was dehydrated in the second step via treatment with acetic anhydride and anhydrous sodium acetate affording N-(4-tolyl)succinimide (2).
In the third step, substituted-2-aminobenzothiazoles were introduced in diazotization reaction with nitrous acid producing the corresponding diazonium salts and these inturn were introduced directly in coupling reaction with compound (2) affording the target cyclic imides (3-7).
Structures of the new compounds were confirmed by depending on FTIR spectral data and (1HNMR and13CNMR) spectra for some of them which were in good agreement with the proposed ones
American Psychological Association (APA)
al-Azzawi, Ahlam Maruf& Jasim, Iman Khalil. 2016. Synthesis and characterization of several new succinimides linked to phenyl azo benzothiazole or thiazole moieties with expected biological activity. Iraqi Journal of Science،Vol. 57, no. 1C, pp.534-544.
https://search.emarefa.net/detail/BIM-688496
Modern Language Association (MLA)
al-Azzawi, Ahlam Maruf& Jasim, Iman Khalil. Synthesis and characterization of several new succinimides linked to phenyl azo benzothiazole or thiazole moieties with expected biological activity. Iraqi Journal of Science Vol. 57, no. 1C (2016), pp.534-544.
https://search.emarefa.net/detail/BIM-688496
American Medical Association (AMA)
al-Azzawi, Ahlam Maruf& Jasim, Iman Khalil. Synthesis and characterization of several new succinimides linked to phenyl azo benzothiazole or thiazole moieties with expected biological activity. Iraqi Journal of Science. 2016. Vol. 57, no. 1C, pp.534-544.
https://search.emarefa.net/detail/BIM-688496
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 542-544
Record ID
BIM-688496